BRCA mutation, mutations in two genes which produce a hereditary breast-ovarian cancer syndrome
BRCA1, the first of these genes to be discovered
BRCA2, the second of these genes to be discovered
British Radio Car Association, a British radio controlled car racing organisation
Brotherhood Railway Carmen of America, a defunct American trade union
Bureau Central de Renseignements et d'Action, the Free French intelligence agency during World War II
Topics referred to by the same term
This disambiguation page lists articles associated with the title BRCA. If an internal link led you here, you may wish to change the link to point directly to the intended article.
Brca or BRCA may refer to: Brca (Bar Municipality), a village in Macedonia BRCA mutation, mutations in two genes which produce a hereditary breast-ovarian...
A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. Hundreds of different types of mutations in these...
the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults. It is a PARP inhibitor, inhibiting...
repair of DNA double-strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk...
The British Radio Car Association (or BRCA) is an organisation that promotes the construction and racing of all types of radio controlled cars in the United...
accessibility of BRCA gene testing and acknowledged the high costs, which were greatly reduced after a 2013 U.S. Supreme Court ruling invalidated BRCA gene patents...
the body, are acquired diseases. Some cancer syndromes, however, such as BRCA mutations, are hereditary genetic disorders. A single-gene disorder (or monogenic...
particularly high risk of developing breast cancer, such as those with a confirmed BRCA mutation, those who have previously had breast cancer, and those with a strong...
marketed by Pfizer for the treatment of advanced breast cancer with germline BRCA mutations. Talazoparib is similar to the first in class PARP inhibitor, olaparib...
of cases are the result of an inherited genetic predisposition, including BRCA mutations among others. Breast cancer most commonly develops in cells from...
Evert underwent a preventative hysterectomy after learning she carried the BRCA gene mutation. Cancer was uncovered in her resected fallopian tubes in 2022...
radio-controlled car when he was five. Hamilton finished second in the national BRCA championship the following year against adult competition. Being the only...
being researched in BRCA-positive and BRCA-negative recurrent advanced ovarian cancer. Niraparib is a PARP inhibitor being tested in BRCA-positive recurrent...
in the death of the child. Another example are the BRCA mutations; inheriting one defective BRCA allele results in a greatly increased risk of breast...
women with substantially increased risk of ovarian cancer, such as high-risk BRCA mutation carriers and women with endometriosis who also have frequent ovarian...
carcinoma shows similar rates of tumor suppressor gene dysfunction (p53, BRCA, WT1) as ovarian cancer and can also show an increased expression of HER-2/neu...
"Prophylactic Salpingectomy and Delayed Oophorectomy as an Alternative for BRCA Mutation Carriers". Obstetrics & Gynecology. 121 (1): 14–24. doi:10.1097/aog...
2017. The couple have one daughter who was born in November 2019. Due to a BRCA mutation that put her at high risk of developing breast cancer, McEnany underwent...
as monotherapy (at 400 mg taken twice per day) for patients with germline BRCA mutated (gBRCAm) advanced ovarian cancer who have been treated with three...