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BRCA information


Brca or BRCA may refer to:

  • Brca (Bar Municipality), a village in Macedonia
  • BRCA mutation, mutations in two genes which produce a hereditary breast-ovarian cancer syndrome
    • BRCA1, the first of these genes to be discovered
    • BRCA2, the second of these genes to be discovered
  • British Radio Car Association, a British radio controlled car racing organisation
  • Brotherhood Railway Carmen of America, a defunct American trade union
  • Bureau Central de Renseignements et d'Action, the Free French intelligence agency during World War II

and 21 Related for: BRCA information

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BRCA

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Brca or BRCA may refer to: Brca (Bar Municipality), a village in Macedonia BRCA mutation, mutations in two genes which produce a hereditary breast-ovarian...

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BRCA mutation

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A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. Hundreds of different types of mutations in these...

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Olaparib

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the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults. It is a PARP inhibitor, inhibiting...

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BRCA1

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repair of DNA double-strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk...

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British Radio Car Association

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The British Radio Car Association (or BRCA) is an organisation that promotes the construction and racing of all types of radio controlled cars in the United...

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Gonad

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Aug;35(8):e21753. doi: 10.1096/fj.202100756R. PMID: 34233068 Turan V, Oktay K. BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging. Hum...

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Angelina Jolie

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accessibility of BRCA gene testing and acknowledged the high costs, which were greatly reduced after a 2013 U.S. Supreme Court ruling invalidated BRCA gene patents...

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Genetic disorder

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the body, are acquired diseases. Some cancer syndromes, however, such as BRCA mutations, are hereditary genetic disorders. A single-gene disorder (or monogenic...

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Breast cancer screening

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particularly high risk of developing breast cancer, such as those with a confirmed BRCA mutation, those who have previously had breast cancer, and those with a strong...

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Talazoparib

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marketed by Pfizer for the treatment of advanced breast cancer with germline BRCA mutations. Talazoparib is similar to the first in class PARP inhibitor, olaparib...

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Breast cancer

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of cases are the result of an inherited genetic predisposition, including BRCA mutations among others. Breast cancer most commonly develops in cells from...

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Canada goose

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Europaea: 96482 Fauna Europaea (new): 9c6f028c-ae4c-44b0-bb10-011ad81b1bdb FEIS: brca GBIF: 5232437 GISD: 1427 GNAB: canada-goose IBC: canada-goose-branta-canadensis...

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Chris Evert

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Evert underwent a preventative hysterectomy after learning she carried the BRCA gene mutation. Cancer was uncovered in her resected fallopian tubes in 2022...

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Lewis Hamilton

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radio-controlled car when he was five. Hamilton finished second in the national BRCA championship the following year against adult competition. Being the only...

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Ovarian cancer

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being researched in BRCA-positive and BRCA-negative recurrent advanced ovarian cancer. Niraparib is a PARP inhibitor being tested in BRCA-positive recurrent...

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Lethal allele

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in the death of the child. Another example are the BRCA mutations; inheriting one defective BRCA allele results in a greatly increased risk of breast...

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Oophorectomy

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women with substantially increased risk of ovarian cancer, such as high-risk BRCA mutation carriers and women with endometriosis who also have frequent ovarian...

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Primary peritoneal carcinoma

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carcinoma shows similar rates of tumor suppressor gene dysfunction (p53, BRCA, WT1) as ovarian cancer and can also show an increased expression of HER-2/neu...

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Salpingectomy

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"Prophylactic Salpingectomy and Delayed Oophorectomy as an Alternative for BRCA Mutation Carriers". Obstetrics & Gynecology. 121 (1): 14–24. doi:10.1097/aog...

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Kayleigh McEnany

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2017. The couple have one daughter who was born in November 2019. Due to a BRCA mutation that put her at high risk of developing breast cancer, McEnany underwent...

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PARP inhibitor

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as monotherapy (at 400 mg taken twice per day) for patients with germline BRCA mutated (gBRCAm) advanced ovarian cancer who have been treated with three...

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