Artificial saliva or salivary substitutes refer to a synthetically produced liquid that mimics the natural secretion of saliva. It is designed as a symptomatic relief for xerostomia, a condition characterised by dryness in the mouth and is available over-the-counter. The efficacy of artificial saliva in a systematic review of clinical trials indicates that all evaluated products reduce xerostomia symptoms, but the comparative effectiveness remains unclear due to study inconsistencies and potential biases. Side effects are uncommon, but users should take precautions against possible side effects such as allergic reactions.
Artificial saliva is mainly composed of bioactive compounds, which substitute for natural saliva's biological functions, such as facilitating antimicrobial activity, digestion and lubrication of oral tissues. Additional components such as buffering and flavouring agents are added to increase the stability of formulations and user acceptance, respectively. These formulations are available in various forms and have varied chemical-physical properties.
Current research on artificial saliva focuses on expanding its functionality by incorporating synthetic molecules similar to their biological counterparts in natural saliva. The study includes efforts to enhance native salivary proteins and synthesise novel molecules using various chemical and genetic engineering techniques.
Artificialsaliva or salivary substitutes refer to a synthetically produced liquid that mimics the natural secretion of saliva. It is designed as a symptomatic...
effective in alleviating or terminating the symptoms. These include artificialsaliva, pilocarpine, zinc supplementation, alterations in drug therapy, and...
the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause. This symptom is...
Streptococcus salivarius growth and maintenance in artificialsaliva: Growth of S. salivarius in saliva". Journal of Applied Microbiology. 111 (3): 631–641...
chemical breakdown by digestive enzymes, that takes place in the mouth. Saliva contains the digestive enzymes amylase, and lingual lipase, secreted by...
chewability. Tablets of sucroferric oxyhydroxide easily disintegrated in artificialsaliva. Clinical Phase III studies showed that sucroferric oxyhydroxide achieves...
"Study of experiment on leaching of bisphenol A from infant books to artificialsaliva". Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene). 65 (3): 467–70...
properties of enamel after microabrasion, polishing, and storage in artificialsaliva". Biomed Mater. 6 (3): 035001. Bibcode:2011BioMa...6c5001F. doi:10...
PMID 30867989. Bao C, Kaur M, Kim WS (2019-04-15). "Toward a highly selective artificialsaliva sensor using printed hybrid field effect transistors". Sensors and...
sperm for artificial insemination or to inseminate using intercourse at the optimum time of the month. One type of ovulation predictor is a saliva tester...
hydrolysis of starch (Latin amylum) into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of...
forms on the surface enamel, dentin, artificial crowns, and bridges by selective binding of glycoproteins from saliva that prevents continuous deposition...
water is somewhat acidic, this acidity can be partially neutralized by saliva. A study found that sparkling mineral water is slightly more erosive to...
or suck on sugarless candy in order to increase the flow of saliva. Some artificialsaliva products may give temporary relief. Men with prostate enlargement...
operates on tooth surfaces: in the mouth, it creates low levels of fluoride in saliva, which reduces the rate at which tooth enamel demineralizes and increases...
stability and interactions of milk-protein-stabilized emulsions in an artificialsaliva". Food Hydrocolloids. 23 (5): 1270–1278. doi:10.1016/J.FOODHYD.2008...
serpents are twisted together in summer, and coiled up in an artificial knot by their saliva and slime; and this is called "the serpent's egg". The druids...
or scratches a human or other animals. Saliva from an infected animal can also transmit rabies if the saliva comes into contact with the eyes, mouth...
the drug development potential of blood-feeding insect saliva. These compounds in the saliva of blood-feeding insects can increase the ease of blood...
sugar-free gum produces saliva to wash away bacteria, which protects teeth. Chewing gum can also help with the lack of saliva or xerostomia since it naturally...
antimicrobial function, like that of earwax or other secretory fluids (e.g., tears, saliva, and milk).[clarification needed] It does this through a combination of...
flow of saliva to help remove food and bacterial debris from the mouth. Like chewing gums and throat lozenges, many breath mints are artificially sweetened...
2007, the son of Weisner and Barton's marriage, Jonathan Wiesner, provided saliva and blood from which his DNA was isolated and held on record. Since then...
Pollack A (7 May 2014). "Researchers Report Breakthrough in Creating Artificial Genetic Code". The New York Times. Retrieved 7 May 2014. Malyshev DA,...
the CITES permitting system. Medicinal leeches have been found to secrete saliva containing about 60 different proteins. These achieve a wide variety of...