This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Other names in common use include sesquiterpene cyclase, trans,trans-farnesyl diphosphate aristolochene-lyase, trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing and aristolochene-forming). This enzyme participates in terpenoid biosynthesis.
This protein may use the morpheein model of allosteric regulation.[1]
^T. Selwood & E. K. Jaffe (2011). "Dynamic dissociating homo-oligomers and the control of protein function". Arch. Biochem. Biophys. 519 (2): 131–43. doi:10.1016/j.abb.2011.11.020. PMC 3298769. PMID 22182754.
and 10 Related for: Aristolochene synthase information
The enzyme aristolochenesynthase (EC 4.2.3.9) catalyzes the chemical reaction (2E,6E)-farnesyl diphosphate ⇌ (+)-aristolochene + diphosphate This enzyme...
roqueforti. It is biosynthesized from farnesyl pyrophosphate by aristolochenesynthase and is the parent hydrocarbon of a large variety of fungal toxins...
pyrophosphate. Crystal structures of recombinant tobacco 5-epi-aristolochenesynthase (TEAS), alone and also complexed with two FPP analogues have been...
cyclase may refer to: Delta-cadinene synthase, an enzyme Aristolochenesynthase, an enzyme Trichodiene synthase, an enzyme This disambiguation page lists...
of transition states prior to and following eudesmane cation in aristolochenesynthase". Organic and Biomolecular Chemistry. 4 (13): 2563–2567. doi:10...
"Purification and characterization of the sesquiterpene cyclase aristolochenesynthase from Penicillium roqueforti". Archives of Biochemistry and Biophysics...
hydrocarbon aristolochene, a sesquiterpene produced from farnesyl diphosphate catalyzed by the enzyme aristolochenesynthase. Aristolochene then gains...
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