Foreign Associate of the National Academy of Sciences
Royal Medal (2008)
Copley Medal (2020)
Scientific career
Fields
Protein folding
p53
Cancer[1]
Institutions
Laboratory of Molecular Biology[2]
University of Cambridge
Imperial College, London
Gonville and Caius College, Cambridge
Thesis
Intramolecular Catalysis of Ester Hydrolysis(1968)
Doctoral students
Jane Clarke[3][4][5]
Sophie E. Jackson, Andreas Matouschek
Sir Alan Roy FershtFRS FMedSci[6] (born 21 April 1943) is a British chemist at the MRC Laboratory of Molecular Biology, Cambridge, and an Emeritus Professor in the Department of Chemistry at the University of Cambridge.[7] He was Master of Gonville and Caius College, Cambridge from 2012 to 2018.[8] He works on protein folding, and is sometimes described as a founder of protein engineering.[9][10]
^Alan Fersht publications indexed by Google Scholar
^Alan Fersht LMB Profile
^Clarke, Jane (1993). Studies of disulphide mutants of barnase. jisc.ac.uk (PhD thesis). University of Cambridge. OCLC 53666398. EThOS uk.bl.ethos.318014. Archived from the original on 22 December 2018. Retrieved 17 June 2019.
^"Women at Cambridge: Jane Clarke". University of Cambridge. 11 February 2014. Archived from the original on 24 March 2015.
^Clarke, J; Fersht, A. R. (1993). "Engineered disulfide bonds as probes of the folding pathway of barnase: Increasing the stability of proteins against the rate of denaturation". Biochemistry. 32 (16): 4322–9. doi:10.1021/bi00067a022. PMID 8476861.
^"Professor Sir Alan Fersht FRS FMedSci". Academy of Medical Sciences. Archived from the original on 17 April 2015.
^"Professor Sir Alan Fersht FRS, Department of Chemistry, University of Cambridge". Retrieved 26 July 2011.
^"Professor Sir Alan Fersht FRS becomes the 42nd Master of Caius". Archived from the original on 22 April 2015. Retrieved 21 November 2012.
^"Imperial College London: biographical summary Alan Fersht". Archived from the original on 27 June 2009.
^BBC: brief Fersht career summary at time of knighthood
Sir Alan Roy Fersht FRS FMedSci (born 21 April 1943) is a British chemist at the MRC Laboratory of Molecular Biology, Cambridge, and an Emeritus Professor...
AlanFersht and Sir Greg Winter. Sir AlanFersht was Director of the MRC CPE from 1990 to 2010, with Greg Winter as Deputy Director. Both, Sir Alan Fersht...
Elvidge, Permanent Secretary to the Scottish Executive 2003-2010 Prof Sir AlanFersht, Herchel Smith Professor of Organic Chemistry at the University of Cambridge...
had been elected the next master of Gonville and Caius, succeeding Sir AlanFersht when he retired in September 2018. She is the college's first female...
Martin Gruebele, Brian Dyer, William Eaton, Sheena Radford, Chris Dobson, AlanFersht, Bengt Nölting and Lars Konermann. Proteolysis is routinely used to probe...
bradykinin potentiating factor, important for anti-hypertension drugs AlanFersht (born 1943), British chemist and biochemist, expert on enzymes and protein...
of surgical products from blood plasma. Member Natl. Acad. Sci. USA. AlanFersht FRS (b. 1943). British chemist and biochemist at the University of Cambridge...
folding of barnase has been extensively studied in the laboratory of AlanFersht, who used it as the test case in developing a method of characterizing...
Binding Systems". Biology LibreTexts. 2013-11-21. Retrieved 2017-02-21. Alan, Fersht (1999). Structure and mechanism in protein science : a guide to enzyme...
of chemical valency; Sir William Crookes, discoverer of thallium; Sir AlanFersht, chemist; David Phillips, chemist; Harold Hopkins, contributed to the...
biochemist, Nobel Prize winner Thomas Campbell Eyton (St John's), naturalist AlanFersht (Caius) Ronald Fisher (Caius) John Flamsteed (Jesus) Howard Florey (Caius)...
Brad Amos Mariann Bienz Richard Anthony Crowther Philip Richard Evans AlanFersht Michael Gait Richard Henderson Rob Kay John Kendrick-Jones John Kilmartin...
S2CID 2527166. Wikimedia Commons has media related to Active site. AlanFersht, Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis...
including his discovery that led to rechargeable lithium batteries." 2020 AlanFersht "He has developed and applied the methods of protein engineering to provide...
photosynthesis mechanisms for plants and bacteria Julio M. Fernandez AlanFersht — pioneered work on protein folding Adolf Eugen Fick — responsible for...
Cambridge In office 2006–2012 Preceded by Neil McKendrick Succeeded by Sir AlanFersht Personal details Born 27 January 1946 (1946-01-27) (age 78) Children...
Bristol in the UK. As a research student he also worked in the lab of Sir AlanFersht in Cambridge, UK at the MRC Laboratory for Molecular Biology (LMB) site...
(died 2000) 20 April – John Eliot Gardiner, English conductor 21 April – AlanFersht, English chemist and academic 24 April – Hew Pike, general 25 April –...
Fran Ashcroft, Chris Dobson, Janet Thornton, Venki Ramakrishnan 2009: AlanFersht, Jean Thomas 2008: Iain Campbell*, John Squire 2007: Jim Barber, Tim...
stabilizing non-native interactions in a transition state facilitates folding. AlanFersht pioneered phi value analysis in his study of the small bacterial protein...
understanding of the role of protein phosphorylation in cell regulation." AlanFersht Chemistry "In recognition of his seminal work in protein engineering...
professor in the College of Natural Sciences. His graduate work with AlanFersht resulted in the seminal application of phi-value analysis to the study...
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