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Medical condition
Acne fulminans
Specialty
Dermatology
Acne fulminans (also known as "acute febrile ulcerative acne"[1]: 686 ) is a severe form of the skin disease, acne, which can occur after unsuccessful treatment for another form of acne, acne conglobata. The condition is thought to be an immunologically induced disease in which elevated level of testosterone causes a rise in sebum and population of Cutibacterium acnes bacteria. The increase in the amount of C acnes or related antigens may trigger the immunologic reaction in some individuals and lead to an occurrence of acne fulminans.[2] In addition to testosterone, isotretinoin may also precipitate acne fulminans, possibly related to highly increased levels of C acnes antigens in the patient's immune system.[3] Acne fulminans is a rare disease. Over the past several years, fewer cases of this disease have occurred, possibly because of earlier and better treatment of acne. Approximately 100 patients with acne fulminans have been described.[4]
^Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^Heydenreich, G. (1989). "Testosterone and anabolic steroids and acne fulminans". Archives of Dermatology. 125 (4): 571–2. doi:10.1001/archderm.1989.01670160119036. ISSN 0003-987X. PMID 2522757.
^Zaba, R.; Schwartz, R.; Jarmuda, S.; Czarnecka-Operacz, M.; Silny, W. (2011). "Acne fulminans: explosive systemic form of acne". Journal of the European Academy of Dermatology and Venereology. 25 (5): 501–7. doi:10.1111/j.1468-3083.2010.03855.x. ISSN 1468-3083. PMID 21029206. S2CID 657256.
Acnefulminans (also known as "acute febrile ulcerative acne": 686 ) is a severe form of the skin disease, acne, which can occur after unsuccessful treatment...
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purpura, malignant chickenpox with purpura, postinfectious purpura, purpura fulminans, and anaphylactoid purpura. These syndromes have variable courses, with...
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