AMG 319 is a drug developed by Amgen which acts as an inhibitor of the phosphoinositide 3-kinase enzyme subtype PI3Kδ. It was originally developed as an anti-inflammatory drug with potential applications in the treatment of autoimmune conditions such as rheumatoid arthritis, but subsequent research showed that it inhibits cell proliferation and might potentially have useful anti-cancer effects, and it has been put into clinical trials to assess its safety and tolerability in this application.[1][2]
^Cushing TD, Hao X, Shin Y, Andrews K, Brown M, Cardozo M, et al. (January 2015). "Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease". Journal of Medicinal Chemistry. 58 (1): 480–511. doi:10.1021/jm501624r. PMID 25469863.
^Lanasa MC, Glenn MJ, Mato AR, Allgood SD, Wong S, Amore B, et al. (December 2013). First-In-Human Study Of AMG 319, a Highly Selective, Small Molecule Inhibitor Of PI3Kδ, In Adult Patients With Relapsed Or Refractory Lymphoid Malignancies. 55th ASH Annual Meeting and Exposition.
AMG319 is a drug developed by Amgen which acts as an inhibitor of the phosphoinositide 3-kinase enzyme subtype PI3Kδ. It was originally developed as...
the Manufacturers' Championship the GTP and GTD Pro classes, and Mercedes-AMG led the GTD Manufacturers' Championship. Porsche Penske Motorsport, Era Motorsport...
Organic Natural Products. Vol. 103. pp. 1–36. doi:10.1007/978-3-319-45541-9_1. ISBN 978-3-319-45539-6. PMID 28120229. Turner SE, Williams CM, Iversen L, Whalley...
John (January 11, 2024). "Lone Star Commits to Endurance Cup With Mercedes-AMG". Sportscar365. John Dagys Media. Retrieved January 11, 2024. Goodwin, Graham...
Serra 87 Mercedes-AMG Team AKKodis ASP Mercedes-AMG GT3 Evo Thomas Drouet Lorenzo Ferrari Maximilian Götz 88 AKKodis ASP Team Mercedes-AMG GT3 Evo Timur Boguslavskiy...
he won Aurum 1006 km endurance race in Lithuania, driving a Mercedes-Benz AMG GT3 Evo. Magnussen's oldest son Kevin is also a racing driver currently competing...
Challenge. The race was won by the SunEnergy1 AKKodis ASP Team entered Mercedes-AMG GT3 Evo driven by Kenny Habul, Jules Gounon and Luca Stolz. Entries were...
rophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole". Bioorganic &...
(Lepidoptera: Acrolepiidae) in North America". The Canadian Entomologist. 139 (3): 319–353. doi:10.4039/n06-098. S2CID 86748199. "Delia antiqua (Meigen): Onion...
Porsche led the GTP and GTD Pro Manufacturers' Championships, with Mercedes-AMG leading the GTD Manufacturers' Championship, with 10 rounds remaining in...
for Human Chromosomes: A History of Discovery. Springer. p. 88. ISBN 978-3-319-26336-6. "The Top 300 of 2021". ClinCalc. Archived from the original on 15...
made car since the Shelby Daytona Coupe won in 1964. Pole Position - #35 AMG-Mercedes - 3:35.544 (Bernd Schneider) Fastest Lap - #28 Toyota Motorsport...
December 2020. Retrieved 1 December 2020. "Mercedes-AMG Petronas F1 Team Announcement". Mercedes-AMG Petronas F1 Team. Archived from the original on 6 February...
40 minutes) was measured in rats with the application of TRPV1 antagonist AMG-9810. The role of TRPV1 in the regulation of body temperature has emerged...
GTD, Trent Hindman subbed for Ben Keating the #33 Riley Motorsports - Team AMG entry due to Hurricane Harvey making landfall affecting Ben's car delaerships...
received a 10 kilogram weight increase. In GTD Pro and GTD, the Mercedes-AMG GT3 Evo and Porsche 911 GT3 R were given weight increases of 20 and 10 kilograms...
laundry detergent industry". Journal of Surfactants and Detergents. 7 (4): 319–328. doi:10.1007/s11743-004-0317-7. S2CID 93889318. Hill, J. A. (22 October...
Thyroid Diseases. Endocrinology. pp. 1–22. doi:10.1007/978-3-319-29456-8_11-1. ISBN 978-3-319-29195-6. Archived from the original on April 7, 2024. Retrieved...
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