60S ribosomal protein L5 information

RPL5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5AJ0, 4UJD, 4D67, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL5, DBA6, L5, PPP1R135, MSTP030, Ribosomal protein L5, uL18
External IDs	OMIM: 603634; MGI: 102854; HomoloGene: 110649; GeneCards: RPL5; OMA:RPL5 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	92,841,924 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	108,056,871 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; gonad; ; parietal pleura; ; epithelium of nasopharynx; ; left ovary; ; tibia; ; right ovary; ; palpebral conjunctiva; ; ventricular zone; ; body of uterus;
	Top expressed in
	epiblast; ; uterus; ; ovary; ; ventricular zone; ; embryo; ; ganglionic eminence; ; embryo; ; lens; ; spermatocyte; ; ileum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	rRNA binding; protein binding; RNA binding; structural constituent of ribosome; mRNA 3'-UTR binding; 5S rRNA binding; ubiquitin protein ligase binding; mRNA 5'-UTR binding; ubiquitin ligase inhibitor activity;
Cellular component	cytoplasm; cytosol; ribosome; membrane; focal adhesion; intracellular anatomical structure; nucleolus; cytosolic large ribosomal subunit; extracellular exosome; nucleus; nucleoplasm; endoplasmic reticulum; protein-containing complex; synapse; ribonucleoprotein complex;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; ribosomal large subunit biogenesis; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; rRNA processing; ribosomal large subunit assembly; protein biosynthesis; positive regulation of gene expression; positive regulation of translation; protein stabilization; negative regulation of ubiquitin protein ligase activity; negative regulation of ubiquitin-dependent protein catabolic process; negative regulation of protein neddylation; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	6125
	100503670
	ENSG00000122406
	ENSMUSG00000058558
	P46777; Q5T7N0
	P47962
	NM_000969
	NM_016980
	NP_000960
	NP_058676
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal protein L5 is a protein that in humans is encoded by the RPL5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122406 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058558 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Qu LH, Nicoloso M, Michot B, Azum MC, Caizergues-Ferrer M, Renalier MH, Bachellerie JP (November 1994). "U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals". Nucleic Acids Res. 22 (20): 4073–81. doi:10.1093/nar/22.20.4073. PMC 331892. PMID 7937132.
^ Frigerio JM, Dagorn JC, Iovanna JL (July 1995). "Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs". Biochim Biophys Acta. 1262 (1): 64–8. doi:10.1016/0167-4781(95)00045-i. PMID 7772601.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000122406 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058558 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7937132-5] Qu LH, Nicoloso M, Michot B, Azum MC, Caizergues-Ferrer M, Renalier MH, Bachellerie JP (November 1994). "U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals". Nucleic Acids Res. 22 (20): 4073–81. doi:10.1093/nar/22.20.4073. PMC 331892. PMID 7937132.

[pmid7772601-6] Frigerio JM, Dagorn JC, Iovanna JL (July 1995). "Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs". Biochim Biophys Acta. 1262 (1): 64–8. doi:10.1016/0167-4781(95)00045-i. PMID 7772601.

60S ribosomal protein L5 information

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