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60S ribosomal protein L21 information


RPL21
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPL21, HYPT12, L21, ribosomal protein L21
External IDsOMIM: 603636; MGI: 1278340; HomoloGene: 128048; GeneCards: RPL21; OMA:RPL21 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000982

NM_019647

RefSeq (protein)

NP_000973

NP_062621

Location (UCSC)Chr 13: 27.25 – 27.26 MbChr 5: 146.77 – 146.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

60S ribosomal protein L21 is a protein that in humans is encoded by the RPL21 gene.[5][6][7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L21E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122026 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041453 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nakamichi NN, Kao FT, Wasmuth J, Roufa DJ (Jul 1986). "Ribosomal protein gene sequences map to human chromosomes 5, 8, and 17". Somat Cell Mol Genet. 12 (3): 225–36. doi:10.1007/BF01570781. PMID 3459254. S2CID 20534231.
  6. ^ Frigerio JM, Dagorn JC, Iovanna JL (Jul 1995). "Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs". Biochim Biophys Acta. 1262 (1): 64–8. doi:10.1016/0167-4781(95)00045-i. PMID 7772601.
  7. ^ a b "Entrez Gene: RPL21 ribosomal protein L21".

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