ZDHHC17 information

ZDHHC17
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EU9
Identifiers
Aliases	ZDHHC17, HIP14, HIP3, HYPH, HSPC294, zinc finger DHHC-type containing 17, DHHC-17, zinc finger DHHC-type palmitoyltransferase 17, DHHC17
External IDs	OMIM: 607799; MGI: 2445110; HomoloGene: 56324; GeneCards: ZDHHC17; OMA:ZDHHC17 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	76,853,696 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	110,846,001 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; cerebellar vermis; ; Brodmann area 23; ; external globus pallidus; ; superior vestibular nucleus; ; subthalamic nucleus; ; pons; ; Achilles tendon; ; middle temporal gyrus; ; germinal epithelium;
	Top expressed in
	cerebellar vermis; ; ascending aorta; ; otolith organ; ; inferior colliculus; ; utricle; ; olfactory tubercle; ; medial dorsal nucleus; ; Region I of hippocampus proper; ; olfactory bulb; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-cysteine S-palmitoyltransferase activity; transferase activity; magnesium ion transmembrane transporter activity; signal transducer activity; palmitoyltransferase activity; protein binding; identical protein binding; acyltransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; intracellular membrane-bounded organelle; membrane; Golgi membrane; Golgi-associated vesicle membrane; cytoplasmic vesicle membrane; cytoplasmic vesicle; presynaptic membrane; plasma membrane; synapse; cell junction; cytosol;
Biological process	protein palmitoylation; positive regulation of I-kappaB kinase/NF-kappaB signaling; lipoprotein transport; signal transduction; magnesium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	23390
	320150
	ENSG00000186908
	ENSMUSG00000035798
	Q8IUH5
	Q80TN5
	NM_015336; NM_001359626
	NM_172554; NM_001359622; NM_001359624
	NP_056151; NP_001346555
	NP_766142; NP_001346551; NP_001346553
	Wikidata
View/Edit Human	View/Edit Mouse

Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by the ZDHHC17 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186908 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035798 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.
^ Goytain A, Hines RM, Quamme GA (Nov 2008). "Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport". The Journal of Biological Chemistry. 283 (48): 33365–74. doi:10.1074/jbc.M801469200. PMC 2662264. PMID 18794299.
^ "Entrez Gene: ZDHHC17 zinc finger, DHHC-type containing 17".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186908 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035798 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9700202-5] Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.

[pmid18794299-6] Goytain A, Hines RM, Quamme GA (Nov 2008). "Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport". The Journal of Biological Chemistry. 283 (48): 33365–74. doi:10.1074/jbc.M801469200. PMC 2662264. PMID 18794299.

[entrez-7] "Entrez Gene: ZDHHC17 zinc finger, DHHC-type containing 17".

ZDHHC17 information

and 4 Related for: ZDHHC17 information

ZDHHC17

Ankyrin repeat

Huntingtin

DHHC domain