Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines.[1] It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural products. It produces tremors in mice due to its neurotoxic properties. It also tested positive in a Salmonella/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated potassium channels.[2]
^Borthwick AD (2012). "2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products". Chemical Reviews. 112 (7): 3641–3716. doi:10.1021/cr200398y. PMID 22575049.
^"Verruculogen from Penicillium verruculosum". sigmaaldrich.com. Retrieved 25 September 2023.
Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated...
estinogenum is an anamorph species of the genus of Penicillium which produces verruculogen. List of Penicillium species MycoBank Straininfo of Penicillium estinogenum...
These are fumitremorgen B, paxilline, penitrem A, verrucosidin, and verruculogen. Trichothecenes – sourced from Cephalosporium, Fusarium, Myrothecium...
fungus in the genus Penicillium which produces griseofulvin, patulin and verruculogen. MycoBank Straininfo of Penicillium raistrickii Sarah De Saeger (2011)...
Penicillium which was isolated from soil in the United States. It produces verruculogen, verrucosidin, verruculotoxin, decalpenic acid, dehydroaltenusin, cyciooctasulfur...
Gallagher, RT; Latch, GC (1977). "Production of the Tremorgenic Mycotoxins Verruculogen and Fumitremorgin B by Penicillium piscarium Westling". Applied and Environmental...