UCA1 information

UCA1
Identifiers
Aliases	UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36, urothelial cancer associated 1 (non-protein coding), urothelial cancer associated 1, UCA1 RNA, human
External IDs	OMIM: 617500; GeneCards: UCA1; OMA:UCA1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	15,836,328 bp
RNA expression pattern
	Top expressed in
	endometrium; ; testicle; ; gallbladder; ; islet of Langerhans; ; placenta; ; urinary bladder; ; epithelium of colon; ; gonad; ; rectum; ; bone marrow;
	n/a
	More reference expression data
	n/a
Orthologs
	652995
	n/a
	ENSG00000214049
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

In molecular biology, Urothelial cancer associated 1 (non-protein coding), also known as UCA1, is a long non-coding RNA, it is upregulated in bladder cancer.^[3] It is believed to function in regulation of embryonic development and in bladder cancer invasion and progression. It regulates the expression of several genes involved in tumourgenesis and/or embryonic development.^[4]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214049 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang XS, Zhang Z, Wang HC, Cai JL, Xu QW, Li MQ, Chen YC, Qian XP, Lu TJ, Yu LZ, Zhang Y, Xin DQ, Na YQ, Chen WF (2006). "Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma" (PDF). Clinical Cancer Research. 12 (16): 4851–8. doi:10.1158/1078-0432.CCR-06-0134. PMID 16914571.
^ Wang F, Li X, Xie X, Zhao L, Chen W (2008). "UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion". FEBS Letters. 582 (13): 1919–27. doi:10.1016/j.febslet.2008.05.012. PMID 18501714. S2CID 207691688.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000214049 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16914571-3] Wang XS, Zhang Z, Wang HC, Cai JL, Xu QW, Li MQ, Chen YC, Qian XP, Lu TJ, Yu LZ, Zhang Y, Xin DQ, Na YQ, Chen WF (2006). "Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma" (PDF). Clinical Cancer Research. 12 (16): 4851–8. doi:10.1158/1078-0432.CCR-06-0134. PMID 16914571.

[pmid18501714-4] Wang F, Li X, Xie X, Zhao L, Chen W (2008). "UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion". FEBS Letters. 582 (13): 1919–27. doi:10.1016/j.febslet.2008.05.012. PMID 18501714. S2CID 207691688.

UCA1 information

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UCA1

Chromosome 19

TBX3