Consensus secondary structure and sequence conservation of Type-P5 twister ribozyme
Identifiers
Symbol
Twister-P5
Rfam
RF02684
Other data
RNA type
Gene; Ribozyme
GO
GO:0003824
SO
SO:0000374
PDB structures
PDBe
The twister ribozyme[1] is a catalytic RNA structure capable of self-cleavage. The nucleolytic activity of this ribozyme has been demonstrated both in vivo and in vitro and has one of the fastest catalytic rates of naturally occurring ribozymes with similar function.[2][3] The twister ribozyme is considered to be a member of the small self-cleaving ribozyme family which includes the hammerhead, hairpin, hepatitis delta virus (HDV), Varkud satellite (VS), and glmS ribozymes.[3]
^Roth A, Weinberg Z, Chen AG, Kim PB, Ames TD, Breaker RR (2013). "A widespread self-cleaving ribozyme class is revealed by bioinformatics". Nat Chem Biol. 10 (1): 56–60. doi:10.1038/nchembio.1386. PMC 3867598. PMID 24240507.
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^ abEiler, Daniel; Wang, Jimin; Steitz, Thomas A. (2014-09-09). "Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme". Proceedings of the National Academy of Sciences. 111 (36): 13028–13033. Bibcode:2014PNAS..11113028E. doi:10.1073/pnas.1414571111. ISSN 0027-8424. PMC 4246988. PMID 25157168.
The twisterribozyme is a catalytic RNA structure capable of self-cleavage. The nucleolytic activity of this ribozyme has been demonstrated both in vivo...
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motif in 2007 and functionally characterized in 2016, or ribozymes like the twisterribozyme, which was detected as an RNA motif and functionally characterized...
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