Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor.[1]
^Wong BK, Woolf TF, Chang T, Whitfield LR (1990). "Metabolic disposition of trimetrexate, a nonclassical dihydrofolate reductase inhibitor, in rat and dog". Drug Metab. Dispos. 18 (6): 980–6. PMID 1981548.
Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor. It has been used with leucovorin in treating pneumocystis pneumonia...
many dihydrofolate reductase inhibitor drugs (such as pyrimethamine, trimetrexate, and piritrexim and the antibiotics Iclaprim and trimethoprim). Some...
medications that are used, alone or in combination, include pentamidine, trimetrexate, dapsone, atovaquone, primaquine, pafuramidine maleate (under investigation)...
Digestive and Kidney Diseases, 2012, PMID 31643237, retrieved 2024-04-11 "Trimetrexate", LiverTox: Clinical and Research Information on Drug-Induced Liver Injury...