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Translational research information


Translational research (also called translation research, translational science, or, when the context is clear, simply translation)[1][2] is research aimed at translating (converting) results in basic research into results that directly benefit humans. The term is used in science and technology, especially in biology and medical science. As such, translational research forms a subset of applied research.

The term has been used most commonly in life sciences and biotechnology, but applies across the spectrum of science and humanities. In the context of biomedicine, translational research is also known as bench to bedside.[3] In the field of education, it is defined as research which translates concepts to classroom practice.

Critics of translational medical research (to the exclusion of more basic research) point to examples of important drugs that arose from fortuitous discoveries in the course of basic research such as penicillin and benzodiazepines. Other problems have stemmed from the widespread irreproducibility thought to exist in translational research literature.

Although translational research is relatively new, there are now several major research centers focused on it. In the U.S., the National Institutes of Health has implemented a major national initiative to leverage existing academic health center infrastructure through the Clinical and Translational Science Awards. Furthermore, some universities acknowledge translational research as its own field to study for a PhD or graduate certificate in.

  1. ^ "Translation Research | NIOSH | CDC". www.cdc.gov. 2020-02-24. Retrieved 2021-11-05.
  2. ^ "What is Translational Research? | UAMS Translational Research Institute". tri.uams.edu. Retrieved 2021-11-05.
  3. ^ Chawla, Bhavna (2018-08-03). "Bench to Bedside: Translational Research Demystified". The Official Scientific Journal of Delhi Ophthalmological Society. 29 (1): 4–5. doi:10.7869/djo.367. S2CID 81524567.

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American Journal of Translational Research

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treatments and predict health outcomes. Translational bioinformatics is a relatively young field within translational research. Google trends indicate the use...

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footbridges to Jacobs Medical Center and the Altman Clinical and Translational Research Institute, a 311,000 gross square feet, $269 million laboratory...

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the AACR focuses on all aspects of cancer research, including basic, clinical, and translational research into the etiology, prevention, diagnosis, and...

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cancer cells, experimental rodents and human health. Preclinical and translational research is aimed at development of new drugs and therapeutics for prevention...

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