TopFIND is the Termini oriented protein Function Inferred Database, a central resource of protein data integrated with knowledge on protein termini, proteolytic processing by proteases, terminal amino acid modifications and inferred functional implications created by combining community contributions with the UniProt and MEROPS databases.
Data types captured
Protein annotation
Organisms
H. sapiens, M. musculus, A. thaliana, S. cerevisiae, E. coli
Contact
Research center
University of British Columbia (UBC), Canada
Laboratory
Christopher Overall
Authors
Philipp F. Lange
Primary citation
TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function[1]
Release date
2011
Access
Data format
Custom comma separated file, SQL, XML.
Website
clipserve.clip.ubc.ca/topfind
Miscellaneous
License
Creative Commons Attribution-NoDerivs
Curation policy
Yes - manual and automatic. Rules for automatic annotation generated by Database Curators and computational algorithms.
TopFIND is the Termini oriented protein Function Inferred Database (TopFIND) is an integrated knowledgebase focused on protein termini, their formation by proteases and functional implications. It contains information about the processing and the processing state of proteins and functional implications thereof derived from research literature, contributions by the scientific community and biological databases.[2]
^Lange, P. F.; Huesgen, P. F.; Overall, C. M. (2011). "TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function". Nucleic Acids Research. 40 (Database issue): D351–D361. doi:10.1093/nar/gkr1025. PMC 3244998. PMID 22102574.
^Lange, P. F.; Overall, C. M. (2011). "TopFIND, a knowledgebase linking protein termini with function". Nature Methods. 8 (9): 703–704. doi:10.1038/nmeth.1669. PMID 21822272. S2CID 7195106.
TopFIND is the Termini oriented protein Function Inferred Database (TopFIND) is an integrated knowledgebase focused on protein termini, their formation...
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