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Timeline of peptic ulcer disease and Helicobacter pylori information


Electron micrograph of H. pylori
Gastric ulcer

This is a timeline of the events relating to the discovery that peptic ulcer disease and some cancers are caused by H. pylori. In 2005, Barry Marshall and Robin Warren were awarded the Nobel Prize in Physiology or Medicine for their discovery that peptic ulcer disease (PUD) was primarily caused by Helicobacter pylori, a bacterium with affinity for acidic environments, such as the stomach. As a result, PUD that is associated with H. pylori is currently treated with antibiotics used to eradicate the infection. For decades prior to their discovery, it was widely believed that PUD was caused by excess acid in the stomach. During this time, acid control was the primary method of treatment for PUD, to only partial success. Among other effects, it is now known that acid suppression alters the stomach milieu to make it less amenable to H. pylori infection.

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Timeline of peptic ulcer disease and Helicobacter pylori

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a timeline of the events relating to the discovery that peptic ulcer disease and some cancers are caused by H. pylori. In 2005, Barry Marshall and Robin...

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Barry Marshall

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bacterium Helicobacter pylori (H. pylori) plays a major role in causing many peptic ulcers, challenging decades of medical doctrine holding that ulcers were...

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Robin Warren

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her death in 1997, Warren retired from medicine. Timeline of peptic ulcer disease and Helicobacter pylori Wikimedia Commons has media related to John Robin...

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discovered in the stratum spinosum of epidermis. Timeline of peptic ulcer disease and Helicobacter pylori Pathology List of pathologists Bizzozero, Giulio...

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John Lykoudis

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companies sufficiently interested in the treatment. Timeline of peptic ulcer disease and Helicobacter pylori Basil Rigas; Chris Feretis; Efstathios D Papavassiliou...

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University of Virginia School of Medicine

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bacterium Helicobacter pylori in the pathogenesis of peptic ulcer disease Alfred G. Gilman, 1994 Nobel Prize in Physiology laureate for discovery of G-proteins...

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(December 2003). "Discovery by Jaworski of Helicobacter pylori and its pathogenetic role in peptic ulcer, gastritis and gastric cancer" (PDF). J. Physiol....

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were responsible for stomach ulcers, gastric cancer and achylia. It was one of the first observations of Helicobacter pylori. He published those findings...

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