Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza.[1][2]
Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells.[3]
Tanshinone I is anti-inflammatory, and modulates or prevents breast cancer metastasis by regulating adhesion molecules.[4]
Tanshinone IIA is anti-inflammatory, an antioxidant, and cytotoxic against a variety of cell lines.[5]
^Lee WY, Cheung CC, Liu KW, et al. (May 2010). "Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells". J. Nat. Prod. 73 (5): 854–9. doi:10.1021/np900792p. PMID 20455578.
^Yoon Y; Kim YO; Jeon WK; Park HJ; Sung HJ (December 1999). "Tanshinone IIA isolated from Salvia miltiorrhiza BUNGE induced apoptosis in HL60 human premyelocytic leukemia cell line". J Ethnopharmacol. 68 (1–3): 121–7. doi:10.1016/S0378-8741(99)00059-8. PMID 10624871.
^Bian, W; Chen, F; Bai, L; Zhang, P; Qin, W (2008). "Dihydrotanshinone I inhibits angiogenesis both in vitro and in vivo". Acta Biochimica et Biophysica Sinica. 40 (1): 1–6. doi:10.1111/j.1745-7270.2008.00370.x. PMID 18180848.
Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring...
(or salvianolic acid B), dihydrotanshinone, miltirone, tanshinone I, and tanshinone IIA. Tanshinone IIA is one of the most abundant constituents of the root...
of many plant monoterpenes and diterpenes such as 8-hydroxygeraniol, tanshinone and alkannin. The first gene identified in this family is the CYP76A1...
biosynthesis (arnebinone and arnebifuranone) and anti-cardiovascular disease (tanshinone). Malbranchea cinnamomea is a thermophilic fungus, which produces a quinone...
12 July 2019. Liu XJ, Wu WT (November 1999). "Effects of ligustrazine, tanshinone II A, ubiquinone, and idebenone on mouse water maze performance". Zhongguo...
Streptomyces pactum Act12 on Salvia miltiorrhiza hairy root growth and tanshinone synthesis and its mechanisms". Applied Biochemistry and Biotechnology...
hydrophobic drugs. Specifically, cationic bovine serum albumin-conjugated tanshinone IIA PEGylated nanoparticles injected into a MCAO rat model decreased the...
recycling counter-current chromatography for natural product isolation: Tanshinones as examples". Journal of Chromatography A. 1327: 27–38. doi:10.1016/j...
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