Triggering receptor expressed on myeloid cells 1 (TREM1) is an immunoglobulin (Ig) superfamily transmembrane protein that, in humans, is encoded by the TREM1 gene.[5][6][7] TREM1 is constitutively expressed on the surface of peripheral blood monocytes and neutrophils, and upregulated by toll-like receptor (TLR) ligands; activation of TREM1 amplifies immune responses.[6][8][9]
^ abcGRCh38: Ensembl release 89: ENSG00000124731 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000042265 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Gingras MC, Lapillonne H, Margolin JF (March 2002). "TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development". Molecular Immunology. 38 (11): 817–24. doi:10.1016/S0161-5890(02)00004-4. PMID 11922939.
^ abBouchon A, Dietrich J, Colonna M (May 2000). "Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes". Journal of Immunology. 164 (10): 4991–5. doi:10.4049/jimmunol.164.10.4991. PMID 10799849.
^"Entrez Gene: TREM1 triggering receptor expressed on myeloid cells 1".
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^Mabbott NA, Baillie J, Brown H, Freeman TC, Hume DA (2013). "An expression atlas of human primary cells: inference of gene function from coexpression networks". BMC Genomics. 14 (1): 632. doi:10.1186/1471-2164-14-632. ISSN 1471-2164. PMC 3849585. PMID 24053356.
myeloid cells 1 (TREM1) is an immunoglobulin (Ig) superfamily transmembrane protein that, in humans, is encoded by the TREM1 gene. TREM1 is constitutively...
activation molecule family member 8), expressed in lymphoid tissues. CD354 TREM1, Triggering receptor expressed on myeloid cells 1. CD355 Cytotoxic and regulatory...
such as defects to toll-like receptor (TLR) 4, IL1 and IL15, TLR3, TLR10, TREM1, VEGFA, DENND1B, and PLAT. The full underlying pathogenesis is not completely...
TREM1, a triggering receptor expressed on myeloid cells 1, a human gene TREM2, a triggering receptor expressed on myeloid cells 2, a human gene Trem Desportivo...
followed by mediated killing [clarification needed] that involves TLR7, and TREM1. Because veto cells can only suppress T-cell progenitors that are directed...
PMID 32023447. S2CID 211047418. Sun H, Feng J, Tang L (December 2020). "Function of TREM1 and TREM2 in Liver-Related Diseases". Cells. 9 (12): 2626. doi:10.3390/cells9122626...
chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and...