transmembrane receptor protein tyrosine kinase adaptor activity
Cellular component
cytoplasm
cytosol
receptor complex
plasma membrane
death-inducing signaling complex
membrane raft
cytoskeleton
nucleus
protein-containing complex
Biological process
extrinsic apoptotic signaling pathway
positive regulation of hair follicle development
regulation of tumor necrosis factor-mediated signaling pathway
tumor necrosis factor-mediated signaling pathway
death-inducing signaling complex assembly
positive regulation of NF-kappaB transcription factor activity
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of extrinsic apoptotic signaling pathway via death domain receptors
I-kappaB kinase/NF-kappaB signaling
activation of cysteine-type endopeptidase activity involved in apoptotic process
extrinsic apoptotic signaling pathway via death domain receptors
signal transduction
apoptotic process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
protein heterooligomerization
positive regulation of cell migration
positive regulation of inflammatory response
cellular response to tumor necrosis factor
positive regulation of NIK/NF-kappaB signaling
transmembrane receptor protein tyrosine kinase signaling pathway
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
8717
71609
Ensembl
ENSG00000102871
ENSMUSG00000031887
UniProt
Q15628
Q3U0V2
RefSeq (mRNA)
NM_003789 NM_153425 NM_001323552
NM_001033161
RefSeq (protein)
NP_001310481 NP_003780
NP_001028333
Location (UCSC)
Chr 16: 67.15 – 67.16 Mb
Chr 8: 105.98 – 105.99 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein that in humans is encoded by the TRADD gene.[5][6]
TRADD is an adaptor protein.
^ abcGRCh38: Ensembl release 89: ENSG00000102871 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000031887 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Hsu H, Xiong J, Goeddel DV (June 1995). "The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation". Cell. 81 (4): 495–504. doi:10.1016/0092-8674(95)90070-5. PMID 7758105. S2CID 14301562.
^"Entrez Gene: TRADD TNFRSF1A-associated via death domain".
DEATH domain protein is a protein that in humans is encoded by the TRADD gene. TRADD is an adaptor protein. The protein encoded by this gene is a death...
Tradd Moore (born October 31, 1987) is an American comic book artist. His work has appeared in series published by Marvel Comics, Image Comics and DC...
book published by Image Comics written by Justin Jordan and with art by Tradd Moore and colors by Felipe Sobreiro. It debuted in October 2011. It features...
Return to Tradd Street January 2014 ISBN 0-451-24059-6 The Guests on a South Battery January 2017 ISBN 978-0451475237 The Christmas Spirits on Tradd Street...
enables the adaptor protein TRADD to bind to the death domain, serving as a platform for subsequent protein binding. Following TRADD binding, three pathways...
Eric Tradd Schneiderman (born December 31, 1954) is an American lawyer and politician who served as the 65th Attorney General of New York from 2011 until...
finds solace in his three roommates, who have become his closest friends: Tradd St. Croix, the son of an upper-class Charlestonian family, and two brawny...
38 Tradd Street, Charleston 1718 House Often described together with adjacent 40 Tradd St. as the Bullock buildings. Bullock Buildings – 40 Tradd Street...
2010 In Treatment Jesse D'Amato 7 episodes At Risk Cal Tradd Television films The Front Cal Tradd Television films 2011 True Blood Timbo 3 episodes 2020...
its receptor TNFR1. TNFR1 binding protein TNFR-associated death protein TRADD and TNF receptor-associated factor 2 TRAF2 signals to RIPK1 which recruits...
3+1⁄2-story, pre-Revolutionary, Georgian Charleston single house at 94 Tradd St., Charleston, South Carolina. The house has tall windows on the first...
historic houses in Charleston, South Carolina. The houses are located north of Tradd St. and south of Elliott St. on East Bay Street, that is, 79 to 107 East...
to have a dedicated office for the handling of the mail, and he used 54 Tradd Street for that purpose. Earlier postmasters handled the mail in their own...
would be expected of the two wrecks. The anomalies were under present-day Tradd Street, so no excavation was done. A post-war letter written by David C...
the intermediate membrane proteins TNF receptor-associated death domain (TRADD) and Fas-associated death domain protein (FADD). cIAP1/2 can inhibit TNF-α...
album Crwth, the world's second CD of crwth music, in 2004 on the Fflach:tradd label. (Meurig also plays with the groups Fernhill and Pigyn Clust.) Other...
is an American comics writer. He is known for co-creating (with artist Tradd Moore) The Strange Talent of Luther Strode and its two sequels (published...
College of Art and Design, where he would meet future artistic collaborators Tradd Moore and Geoff Shaw. Cates majored in sequential art, but left the school...
created by writer/artist Felipe Smith and designed by Smith and artist Tradd Moore. Michael Badilino, an ex-member of the New York City Police Department...
the brick wing was separated from the house and given the address of 109 Tradd Street, but it retained its architectural integrity. It is believed to have...
The special bottling was created in collaboration with the comic artist Tradd Moore and is limited to 400 bottles. Ardbeg inspired the Finnish composer...
which records and releases music by new rock and pop bands; and fflach:tradd, formed in 1997, which records and releases traditional music, specialising...
In addition, most TNF receptors require specific adaptor protein such as TRADD, TRAF, RIP and FADD for downstream signalling. TNF receptors are primarily...
Global Information
