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TAAR2 information


TAAR2
Identifiers
AliasesTAAR2, GPR58, taR-2, trace amine associated receptor 2, trace amine associated receptor 2 (gene/pseudogene)
External IDsOMIM: 604849 MGI: 2685071 HomoloGene: 110760 GeneCards: TAAR2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001033080
NM_014626

NM_001007266

RefSeq (protein)

NP_001028252
NP_055441

NP_001007267

Location (UCSC)Chr 6: 132.62 – 132.62 MbChr 10: 23.81 – 23.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2 gene.[5][6][7][8] TAAR2 is coexpressed with Gα proteins;[8] however, as of February 2017, its signal transduction mechanisms have not been determined.[8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146378 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059763 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, et al. (February 2000). "Cloning and characterization of additional members of the G protein-coupled receptor family". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1490 (3): 311–23. doi:10.1016/s0167-4781(99)00241-9. PMID 10684976.
  6. ^ Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (March 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics. 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104.
  7. ^ "Entrez Gene: TAAR2 trace amine associated receptor 2".
  8. ^ a b c Davenport AP, Alexander S, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga C, Battey J, Benya RV, Jensen RT, Karnik S, Kostenis E, Spindel E, Storjohann L, Tirupula K, Bonner TI, Neubig R, Pin JP, Spedding M, Harmar A (25 June 2015). "TAAR2". IUPHAR/BPS Guide to PHARMACOLOGY. International Union of Basic and Clinical Pharmacology. Retrieved 22 February 2017.

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