Sultamicillin, sold under the brand name Unasyn among others, is an oral form of the penicillin antibiotic combination ampicillin/sulbactam. It is used for the treatment of bacterial infections of the upper and lower respiratory tract, the kidneys and urinary tract, skin and soft tissues, among other organs. It contains esterified ampicillin and sulbactam.[1]
Sultamicillin is better absorbed from the gut than ampicillin/sulbactam, decreasing the chances of diarrhea and dysentery. The inclusion of sulbactam extends ampicillin's spectrum of action to beta-lactamase producing strains of bacteria.[2] Oral sulbactam with the intravenous form provides a regimen of continuous sulbactam therapy throughout the treatment, resulting in better clinical results.[citation needed]
It was patented in 1979 and approved for medical use in 1987.[3]
^Mutschler E (2013). Arzneimittelwirkungen (in German) (10 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 745, 748. ISBN 978-3-8047-2898-1.
^Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 491. ISBN 978-3-527-60749-5.
Sultamicillin, sold under the brand name Unasyn among others, is an oral form of the penicillin antibiotic combination ampicillin/sulbactam. It is used...
medication of the penicillin antibiotic combination ampicillin/sulbactam Sultamicillin, an oral form of the penicillin antibiotic combination ampicillin/sulbactam...
can have activity against VRE. VRE can be successfully treated with sultamicillin. Ryan KJ, Ray CG, Sherris JC (2004). Sherris Medical Microbiology (4th ed...
is on the World Health Organization's List of Essential Medicines. Sultamicillin — esterified ampicillin/sulbactam. Alpha-GPC — choline and glycerophosphate...