This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages)
This biographical article is written like a résumé. Please help improve it by revising it to be neutral and encyclopedic.(April 2024)
This article may rely excessively on sources too closely associated with the subject, potentially preventing the article from being verifiable and neutral. Please help improve it by replacing them with more appropriate citations to reliable, independent, third-party sources.(April 2024) (Learn how and when to remove this message)
(Learn how and when to remove this message)
Stuart L. Schreiber
Born
(1956-02-06) February 6, 1956 (age 68)
Alma mater
University of Virginia Harvard University
Known for
Organic Synthesis Chemical Biology Human Biology Therapeutics Discovery
Awards
Arthur C. Cope Award (2015) Wolf Prize (2016)
Scientific career
Fields
Chemical Biology
Institutions
Yale University Harvard University Broad Institute
Thesis
I: Oxidation of tertiary amines / II: Peroxides in organic synthesis(1981)
Doctoral advisor
Robert Burns Woodward Yoshito Kishi
Stuart Schreiber is an American chemist who is the Morris Loeb Research Professor at Harvard University,[1] a co-Founder of the Broad Institute,[2] Howard Hughes Medical Institute Investigator, Emeritus,[3] and a member of the National Academy of Sciences[4] and National Academy of Medicine.[5] He currently leads Arena BioWorks.
His work integrates chemical biology and human biology to advance the science of therapeutics. Key advances include the discovery that small molecules can function as “molecular glues” that promote protein–protein interactions, the co-discovery of mTOR and its role in nutrient-response signaling, the discovery of histone deacetylases and (with Michael Grunstein and David Allis) the demonstration that chromatin marks regulate gene expression, the development and application of diversity-oriented synthesis to microbial therapeutics, and the discovery of vulnerabilities of cancer cells linked to genetic, lineage and cell-state features, including ferroptotic vulnerabilities. His awards include the Wolf Prize in Chemistry and the Arthur Cope Award. His approach to discovering new therapeutics guided many biotechnology companies that he founded, including Vertex Pharmaceuticals and Ariad Pharmaceuticals. He has founded or co-founded 14 biotechnology companies, which have developed 16 first-in-human approved drugs or advanced clinical candidates.
^"Stuart L. Schreiber". chemistry.harvard.edu. Retrieved 2023-11-29.
^"Stuart L. Schreiber". Broad Institute. 2015-11-23. Retrieved 2023-11-29.
StuartSchreiber is an American chemist who is the Morris Loeb Research Professor at Harvard University, a co-Founder of the Broad Institute, Howard Hughes...
Isaac Liev Schreiber (/ˈliːɛv ˈʃraɪbər/ LEE-ev SHRY-bər; born October 4, 1967) is an American actor, director, screenwriter, and producer. He became known...
Massachusetts. Having attracted notable scientists, the institute is led by StuartSchreiber. The institute has $500 million in initial private funding backed by...
(Colorado State), Harry Wasserman (Yale), Yoshito Kishi (Harvard), StuartSchreiber (Harvard), William R. Roush (Scripps-Florida), Steven A. Benner (UF)...
Harvard University as a doctoral researcher, where she worked alongside StuartSchreiber on strategies to understand the interactions between proteins and molecules...
Nutrition Science Crusade". Wired. Taubes, Gary. (April 13, 2011). Is Sugar Toxic?. The New York Times. Discusses work of StuartSchreiber. Official website...
synthesis, phage-assisted directed evolution and Cas9/CRISPR base-editing. StuartSchreiber is director of the Chemical Biology program. He has developed systematic...
immune response. In the late 1980s and early 1990s Crabtree, along with StuartSchreiber further defined the Ca2+/calcineurin/ NFAT signaling pathway, which...
v t e ACS Chemical Biology Lectureship Alanna Schepartz (2010) StuartSchreiber (2011) Carolyn Bertozzi (2012) Wilfred A. van der Donk (2013) Peter B....
John Backus; polar explorer Richard Byrd; scientists Walter Reed, StuartSchreiber, Daniel Barringer, Richard Lutz, and Francis Collins; artists Edgar...
v t e ACS Chemical Biology Lectureship Alanna Schepartz (2010) StuartSchreiber (2011) Carolyn Bertozzi (2012) Wilfred A. van der Donk (2013) Peter B....
v t e ACS Chemical Biology Lectureship Alanna Schepartz (2010) StuartSchreiber (2011) Carolyn Bertozzi (2012) Wilfred A. van der Donk (2013) Peter B....
our dominion over the interface of chemistry, biology and medicine. StuartSchreiber United States for pioneering chemical insights into the logic of signal...
he remained in the Chemistry Department for his Ph.D., working with StuartSchreiber. He received postdoctoral training with Linda B. Buck, where he characterized...
School. In 2004, he started the Ph.D. Program in Chemical Biology with StuartSchreiber and Greg Verdine. He also created, and continues to teach, a popular...
Thomas A. Saunders III 1967 Darden Chairman of The Heritage Foundation StuartSchreiber 1977 Col Chemical biologist; founding member of the Broad Institute...
to Harvard University as a postdoctoral fellow in the laboratory of StuartSchreiber, where she worked on a diversity oriented synthesis of macrocycles...
United States Broad Institute Massachusetts Institute of Technology StuartSchreiber (born 1956) United States Harvard University Howard Hughes Medical...
Gray Lab permanently moved to Stanford University, that was stated by StuartSchreiber, co-founder of Broad Institute as "Stanford's huge gain". Gray grew...
completing his doctorate degree, Stockwell worked in the laboratory of StuartSchreiber where he spent eighteen months unsuccessfully investigating a molecule...