"SpA" redirects here. For the Italian type of company, see Società per azioni. For other uses, see SPA (disambiguation).
Medical condition
Spondyloarthropathy
Specialty
Rheumatology
Spondyloarthropathy or spondyloarthrosis refers to any joint disease of the vertebral column. As such, it is a class or category of diseases rather than a single, specific entity. It differs from spondylopathy, which is a disease of the vertebra itself, but many conditions involve both spondylopathy and spondyloarthropathy.
Spondyloarthropathy with inflammation is called axial spondyloarthritis.[1] In the broadest sense, the term spondyloarthropathy includes joint involvement of vertebral column from any type of joint disease, including rheumatoid arthritis and osteoarthritis, but the term is often used for a specific group of disorders with certain common features, which are often specifically termed seronegative spondylarthropathies. They have an increased incidence of HLA-B27, as well as negative rheumatoid factor and ANA. Enthesopathy is also sometimes present in association with seronegative spondarthritides[clarify].
Non-vertebral signs and symptoms of degenerative or other not directly infected inflammation, in the manner of spondyloarthropathies, include asymmetric peripheral arthritis (which is distinct from rheumatoid arthritis), arthritis of the toe interphalangeal joints, sausage digits, Achilles tendinitis, plantar fasciitis, costochondritis, iritis, and mucocutaneous lesions. But lower back pain is the most common clinical presentation of the causes of spondyloarthropoathies; this back pain is unique because it decreases with activity.[citation needed]
and spondyloarthropathy. Spondyloarthropathy with inflammation is called axial spondyloarthritis. In the broadest sense, the term spondyloarthropathy includes...
contrast, a spondyloarthropathy is a condition involving the vertebral joints, but many conditions involve both spondylopathy and spondyloarthropathy. Examples...
illnesses, such as sarcoidosis, amyloidosis, ischemia, neoplasms, spondyloarthropathies, vasculitides, drug-related conditions, and eosinophilic enteritis...
from medical imaging and blood tests. AS is a type of seronegative spondyloarthropathy, meaning that tests show no presence of rheumatoid factor (RF) antibodies...
and posterior vertebral endplates in patients with an inflammatory spondyloarthropathy – such as ankylosing spondylitis or an enteropathic arthropathy....
showing that the animals had survived these injuries. Likewise, spondyloarthropathy has also been identified in woolly mammoth remains. An extra number...
MOR 571, might have been a paleopathology, an instance of the disease spondyloarthropathy, but in 1997 it was concluded that it was more likely a normal ontogenetic...
affected individuals. It is classified as a type of seronegative spondyloarthropathy. Genetics are thought to be strongly involved in the development...
spondylitis, this type of arthritis is categorized as a seronegative spondyloarthropathy. Other gastrointestinal disorders like Whipple's disease, celiac...
Extraarticular Features of the Connective Tissue Diseases and the Spondyloarthropathies". Clinical Methods - The History, Physical, and Laboratory Examinations...
sternocostoclavicular hyperostosis, pustulotic arthro-osteitis, and acne-associated spondyloarthropathy. The term SAPHO (an acronym for synovitis, acne, pustulosis, hyperostosis...
is inflammation within the sacroiliac joint. It is a feature of spondyloarthropathies, such as axial spondyloarthritis (including ankylosing spondylitis)...
is known to be associated with other autoimmune diseases, like spondyloarthropathies and psoriasis (thought to often precede psoriatic arthritis). A...
(AS). The BASDAI is one of a group of classification criteria for spondyloarthropathies. The BASDAI consists of a 0 - 10 scale measuring discomfort, pain...
association with autoimmunity. Serum sickness A hypersensitivity. Spondyloarthropathy No consistent evidence of association with autoimmunity. Sweet's...
bone, among other regions. Enthesopathies may take the form of spondyloarthropathies (joint diseases of the spine) such as ankylosing spondylitis, or...
osteoarthritis versus other entities such as rheumatoid arthritis and spondyloarthropathies. Severe osteoarthritis and osteopenia of the carpal joint and 1st...
Diagnostic and Classification Criteria", Ankylosing Spondylitis and the Spondyloarthropathies, Philadelphia: Mosby, pp. 132–144, ISBN 978-0-323-03104-2, retrieved...
have been cathemeral, active throughout the day at short intervals. Spondyloarthropathy has been documented in the spine of a 78-million year old hadrosaurid...
enthesopathy or enthesitis. Enthetic degeneration is characteristic of spondyloarthropathy and other pathologies. The enthesis is the primary site of disease...
pulmonary fibrosis, biliary cirrhosis, various vasculitides, pseudogout, spondyloarthropathy, calcinosis, scleroderma, and amyloidosis. Research regarding the...