Global InformationSpondweni virus information
| Spondweni virus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Kitrinoviricota |
| Class: | Flasuviricetes |
| Order: | Amarillovirales |
| Family: | Flaviviridae |
| Genus: | Flavivirus (?) |
| Virus: | Spondweni virus
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Spondweni virus (SPOV or SPONV) is an arbovirus, or arthropod-borne virus, which is a member of the family Flaviviridae and the genus Flavivirus.[1][2] It is part of the Spondweni serogroup which consists of the Sponweni virus and the Zika virus (ZIKV).[1][3] The Spondweni virus was first isolated in Nigeria in 1952, and ever since, SPONV transmission and activity have been reported throughout Africa.[4][1] Its primary vector of transmission is the sylvatic mosquito Aedes circumluteolus, though it has been isolated from several different types of mosquito.[1] Transmission of the virus into humans can lead to a viral infection known as Spondweni fever, with symptoms ranging from headache and nausea to myalgia (muscle pain) and arthralgia (joint pain).[1][3] However, as SPONV is phylogenetically close to the ZIKV, it is commonly misdiagnosed as ZIKV along with other viral illnesses.[1][3]
- ^ a b c d e f Haddow AD, Nasar F, Guzman H, Ponlawat A, Jarman RG, Tesh RB, et al. (2016) Genetic Characterization of Spondweni and Zika Viruses and Susceptibility of Geographically Distinct Strains of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus (Diptera: Culicidae) to Spondweni Virus. PLoS Negl Trop Dis 10(10): e0005083. https://doi.org/10.1371/journal.pntd.0005083
- ^ Wolfe MS, Calisher CH, McGuire K. Spondweni virus infection in a foreign resident of Upper Volta. Lancet. 1982 Dec 11;2(8311):1306–8. doi: http:// dx.doi.org/10.1016/S0140-6736(82)91511-2 PMID 6128599
- ^ a b c Haddow AD, Woodall JP (2016) Distinguishing between Zika and Spondweni viruses. Bull World Health Organ. 94: 711.
- ^ MacNamara FN. Zika virus: a report on three cases of human infection during an epidemic of jaundice in Nigeria. Trans R Soc Trop Med Hyg. 1954 Mar;48(2):139–45. doi: https://dx.doi.org/10.1016/0035-9203(54)90006-1 PMID 13157159