US 1 / US 78 / US 278 / SC 125 southwest of Clearwater
North end
US 1 / US 78 in Aiken
Location
Country
United States
State
South Carolina
Counties
Aiken
Highway system
South Carolina State Highway System
Interstate
US
State
Scenic
← SC 420
→ SC 430
South Carolina Highway 421 (SC 421) is a 10.360-mile (16.673 km) state highway in the U.S. state of South Carolina. It is an alternate route to U.S. Route 1 (US 1) and US 78 between North Augusta and Aiken.
^"Highway Logmile Report". South Carolina Department of Transportation. Retrieved November 11, 2020.
and 16 Related for: South Carolina Highway 421 information
SouthCarolinaHighway421 (SC 421) is a 10.360-mile (16.673 km) state highway in the U.S. state of SouthCarolina. It is an alternate route to U.S. Route 1...
with US 421 Business, NC 18 and NC 268 in North Wilkesboro. NC 115 was established between 1929 and 1930 by the North Carolina State Highway Commission...
North CarolinaHighway 133 (NC 133) is a primary state highway in the U.S. state of North Carolina. It traverses 46.6 miles (75.0 km) from Oak Island Drive...
Interstate Highway System that travels 2,556.61 miles (4,114.46 km) from Barstow, California, to Wilmington, North Carolina. In North Carolina, I-40 travels...
Interstate Highway in the state of SouthCarolina, linking the state with important transportation and business hubs to the north, west, and south, including...
North CarolinaHighway 268 (NC 268) is a primary state highway in the U.S. state of North Carolina. It connects many communities as it traverses through...
state highways in SouthCarolina. These state highways are owned and maintained by the U.S. state of SouthCarolina, through the SouthCarolina Department...
North CarolinaHighway 18 (NC 18) is a primary state highway in the U.S. state of North Carolina. Traveling north–south through the Foothills region,...
North CarolinaHighway 55 (NC 55) is a primary state highway in the U.S. state of North Carolina. It serves as a traffic artery connecting Durham with...
CarolinaHighway 68 (NC 68) is a north–south state highway in North Carolina. It serves as a connector between Interstate 40 (I-40)/ U.S. Route 421 (US 421)...
North CarolinaHighway 87 (NC 87) is a primary state highway in the U.S. state of North Carolina. NC 87 begins in the Atlantic coastal town of Southport...
Route 221 (US 221) and NC 194. The highway also doubles as a truck route for US 221 (south of US 221 in Boone), US 321 and US 421 (both north of NC 105 Bypass...
Highway System that runs from Montgomery, Alabama, to Petersburg, Virginia. In North Carolina, I-85 travels 231.23 miles (372.13 km) from the South Carolina...
North CarolinaHighway 67 (NC 67) is a 40.9-mile-long (65.8 km) primary state highway in the U.S. state of North Carolina. The highway travels through...
North CarolinaHighway 24 (NC 24) is the longest primary state highway in the U.S. state of North Carolina. It travels east–west between the Charlotte...
North CarolinaHighway 16 (NC 16) is a 143.8-mile (231.4 km) primary state highway in the U.S. state of North Carolina. Traveling in a north–south direction...