Solute carrier organic anion transporter family member 1B3 (SLCO1B3) also known as organic anion-transporting polypeptide 1B3 (OATP1B3) is a protein that in humans is encoded by the SLCO1B3 gene.[5]
OATP1B3 is a 12-transmembrane domain influx transporter. Normally expressed in the liver, the transporter functions to uptake large, non-polar drugs and hormones from the portal vein.
^ abcGRCh38: Ensembl release 89: ENSG00000111700 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000030236 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Members of the Organo AnionTransporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters'...