Solute carrier organic anion transporter family member 1A2 is a protein that in humans is encoded by the SLCO1A2 gene.[5][6]
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000084453 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000063975 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kullak-Ublick GA, Beuers U, Meier PJ, Domdey H, Paumgartner G (Apr 1997). "Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization". J Hepatol. 25 (6): 985–7. doi:10.1016/S0168-8278(96)80307-2. PMID 9007731.
Solutecarrierorganicaniontransporterfamilymember1A2 is a protein that in humans is encoded by the SLCO1A2 gene. This gene encodes a sodium-independent...
Members of the Organo AnionTransporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters'...