dentate gyrus of hippocampal formation granule cell
superior frontal gyrus
muscle of thigh
magnocellular part of medial dorsal nucleus
internal pyramidal layer of neocortex
facial motor nucleus
vestibular membrane of cochlear duct
skeletal muscle tissue
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
metal ion binding
SUMO polymer binding
Cellular component
nucleus
Biological process
cochlea development
hearing
inner ear morphogenesis
cognition
locomotory behavior
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
55084
109205
Ensembl
ENSG00000112320
ENSMUSG00000038248
UniProt
A7XYQ1
Q0P5V2
RefSeq (mRNA)
NM_018013
NM_175407
RefSeq (protein)
NP_060483
NP_780616
Location (UCSC)
Chr 6: 107.49 – 107.66 Mb
Chr 10: 42.88 – 43.05 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Sine oculis-binding protein homolog (SOBP) also known as Jackson circler protein 1 (JXC1) is a protein that in humans is encoded by the SOBP gene.[5][6][7] The first SOBP gene was identified in Drosophila melanogaster in a yeast two-hybrid screen that used the SIX domain of the Sine oculis protein as bait.[8] In most genomes, which harbor SOBP, the gene is present as a single copy.
^ abcGRCh38: Ensembl release 89: ENSG00000112320 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000038248 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: sine oculis binding protein homolog (Drosophila)".
^Birk, E.; Har-Zahav, A.; Manzini, C. M.; Pasmanik-Chor, M.; Kornreich, L.; Walsh, C. A.; Noben-Trauth, K.; Albin, A.; Simon, A. J.; Colleaux, L.; Morad, Y.; Rainshtein, L.; Tischfield, D. J.; Wang, P.; Magal, N.; Maya, I.; Shoshani, N.; Rechavi, G.; Gothelf, D.; Maydan, G.; Shohat, M.; Basel-Vanagaite, L. (2010). "SOBP is Mutated in Syndromic and Nonsyndromic Intellectual Disability and is Highly Expressed in the Brain Limbic System". The American Journal of Human Genetics. 87 (5): 694–700. doi:10.1016/j.ajhg.2010.10.005. PMC 2978971. PMID 21035105.
^Chen, Z.; Montcouquiol, M.; Calderon, R.; Jenkins, N. A.; Copeland, N. G.; Kelley, M. W.; Noben-Trauth, K. (2008). "Jxc1/Sobp, Encoding a Nuclear Zinc Finger Protein, is Critical for Cochlear Growth, Cell Fate, and Patterning of the Organ of Corti". Journal of Neuroscience. 28 (26): 6633–41. doi:10.1523/JNEUROSCI.1280-08.2008. PMC 2556235. PMID 18579736.
^Kenyon KL, Li DJ, Clouser C, Tran S, Pignoni F (November 2005). "Fly SIX-type homeodomain proteins Sine oculis and Optix partner with different cofactors during eye development". Dev. Dyn. 234 (3): 497–504. doi:10.1002/dvdy.20442. PMID 15937930. S2CID 11462221.
protein homolog (SOBP) also known as Jackson circler protein 1 (JXC1) is a protein that in humans is encoded by the SOBP gene. The first SOBP gene was identified...
Putera Sports School (SOBP) which has begun its activities for football sports since April 2016 in the city of Banjarmasin. SOBP has been initiated as...
range; this maximum is called the spread out Bragg peak, often called the SOBP (see visual). To treat tumors at greater depth, one needs a beam with higher...
modifying the proton beam is referred to as the spread out Bragg Peak, or SOBP, which allows the treatment to conform to not only larger tumors, but to...
2010– Dec 2020) 2022 – George M Thompson Award for Distinguished Service, SOBP Women's Leadership Group (team award) 2022 – 33rd H.W. Magoun Annual Distinguished...
contributions to biomedical communication The 2006 Society of Biological Psychiatry (SOBP): Gold Medal Award for lifetime research The 2003 National Alliance for the...
Global Information
