Situs inversus causes the positions of the heart and lungs to be mirrored.
Specialty
Medical genetics
Causes
Genes
Frequency
0.01%
Situs inversus (also called situs transversus or oppositus) is a congenital condition in which the major visceral organs are reversed or mirrored from their normal positions. The normal arrangement of internal organs is known as situs solitus. Although cardiac problems are more common, many people with situs inversus have no medical symptoms or complications resulting from the condition, and until the advent of modern medicine, it was usually undiagnosed.
Situs inversus is found in about 0.01% of the population, or about 1 person in 10,000. In the most common situation, situs inversus totalis, it involves complete transposition (right to left reversal) of all of the viscera. The heart is not in its usual position in the left chest, but is on the right, a condition known as dextrocardia (literally, "right-hearted"). Because the relationship between the organs is not changed, most people with situs inversus have no associated medical symptoms or complications.[1]
An uncommon form of situs inversus is isolated levocardia, in which the position of the heart is not mirrored alongside the other organs. Isolated levocardia carries a risk of heart defects, and so patients with the condition may require surgery to correct them.
In rarer cases such as situs ambiguus or heterotaxy, situs cannot be determined. In these patients, the liver may be midline, the spleen absent or multiple, and the bowel malrotated. Often, structures are duplicated or absent altogether. This is more likely to cause medical problems than situs inversus totalis.[2]
^"Definition of Situs inversus totalis". MedicineNet. Archived from the original on 2019-02-02. Retrieved 2015-05-12.
of internal organs is known as situs solitus. Although cardiac problems are more common, many people with situsinversus have no medical symptoms or complications...
the chest. Situs solitus describes viscera that are in the normal position, with the stomach on the left side. Dextrocardia situsinversus refers to the...
Complete reversal of all organs is known as situsinversus, while reversal of some organs but not others is called situs ambiguus or heterotaxy. Isolated reversal...
placement. Situsinversus is the mirror image of situs solitus, which is normal asymmetric distribution of the abdominothoracic visceral organs. Situs ambiguus...
Situsinversus (also called situs transversus or oppositus) is a congenital condition in which the major visceral organs are reversed or mirrored from...
corpus callosum Anencephaly or other neural tube defects Organ systems Situsinversus (full rotation of the internal organs) Cardiac anomalies Ambiguous genitalia...
biology, situs refers to the disposition of organs in organisms with left-right asymmetry Situs solitus, the normal position of organs Situsinversus, the...
called situs ambiguus or heterotaxy, where organ placement or development is neither typical (situs solitus) nor totally reversed (situsinversus totalis)...
visceral organs, which can be in situs solitus, where the remainder of the organs are on normal side as well; or situsinversus, in which the viscera (stomach...
Isolated levocardia (also known as situsinversus with levocardia) is a rare type of organs' situsinversus in which the heart is still in normal position...
supply these organs would need to be rearranged should a normal, non situsinversus (situs solitus) organ be required. In the monocot bloodroot family, the...
possible the pain could localize to the left lower quadrant in people with situsinversus totalis. The combination of migrated umbilical pain to the right lower...
LRRTM1 In heart Levocardia Dextrocardia In major viscera Situs solitus Situs ambiguus Situsinversus In feet Footedness Footedness in boardsports Regular...
LRRTM1 In heart Levocardia Dextrocardia In major viscera Situs solitus Situs ambiguus Situsinversus In feet Footedness Footedness in boardsports Regular...
common on the right side of the spine. In people with dextrocardia and situsinversus this calcification occurs on the left side. Examples of DISH Confluent...
Asphyxiating thoracic dysplasia (ATD), also known as Jeune syndrome, is a rare inherited bone growth disorder (autosomal recessive skeletal dysplasia)...
right in dextrocardia, in which the heart is found on the right, or situsinversus, in which the location of all organs are flipped.: 188 Variations in...
and rectal fistula Meckel’s diverticulum, intestinal malrotation, and situsinversus Genitourinary tract anomalies Duplication of external and internal genitalia...
left side. In rare cases, when organs are reversed as is the case in situsinversus, resonant (hollow) sounds would be expected on the right side and liver...
LRRTM1 In heart Levocardia Dextrocardia In major viscera Situs solitus Situs ambiguus Situsinversus In feet Footedness Footedness in boardsports Regular...
with first identifying transposition of the great vessels (TGV) and situsinversus. He was born in the manse at Shotts in Lanarkshire, the son of Rev Prof...
for congenital heart disease and usually occurs simultaneously with situsinversus, asplenia, or polysplenia, persistent left superior vena cava (SVC)...
anatomic abnormalities such as situsinversus (a combination of findings is known as Kartagener syndrome), and situs ambiguus (also known as Heterotaxy...
patients are susceptible to GI issues and may need further surgery. Situsinversus, a congenital condition in which the major visceral organs are reversed...
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