Anne of Denmark mourning the death of her son Henry in 1612
Differential diagnosis
hypothyroidism
The Sign of Hertoghe or Queen Anne's sign is a thinning or loss of the outer third of the eyebrows, and is a classical sign of hypothyroidism or atopic dermatitis,[1][2][3] but it can also be detected in lepromatous leprosy.[4] The sign is named after the Belgian Internist Eugene Ludovic Christian Hertoghe (April 5, 1860–January 3, 1928), who was a native of Antwerp, and was the first pioneer in thyroid function research.[2][3][5]
^Ständer, Sonja (2021-03-25). "Atopic Dermatitis". New England Journal of Medicine. 384 (12): 1136–1143. doi:10.1056/NEJMra2023911. PMID 33761208. S2CID 232355341.
^ abSchatz, Henry A. (May 1922). "The Role of the Thyroid Gland in Otolaryngology". The Pennsylvania Medical Journal. 25 (8): 529.
^ ab"Complimentary Dinner given by Dr. William Seaman Bainbridge". American Medicine. 9 (4): 308. April 1914. Retrieved 2014-12-12.
^Parrino, Daniela; Di Bella, Stefano (2016-03-29). "Hertoghe sign: an hallmark of lepromatous leprosy". QJM: Monthly Journal of the Association of Physicians. 109 (7): 497. doi:10.1093/qjmed/hcw046. ISSN 1460-2393. PMID 27026695.
^"Eugène Ludovic Christian Hertoghe (1860-1928) » van Lerberghe genealogy » Genealogy Online".
The SignofHertoghe or Queen Anne's sign is a thinning or loss of the outer third of the eyebrows, and is a classical signof hypothyroidism or atopic...
Palace. Cape Ann, Massachusetts SignofHertoghe Anne of Denmark and contrary winds Letter from Queen Anne to the Duke of Buckingham, Folger Shakespeare...
and a printing house to spread the news of the savior Jesus Christ. In 1900, with Father Belpaire and Ch. Hertoghe, Henry Le Grelle founded a bakery cooperative...