Sergei Sergeevich Mukhanov (Russian: Сергей Сергеевич Муха́нов; Polish: Siergiej Siergiejewicz Muchanow; 1833, Vologda, Russian Empire – May 29, 1897, Przemęczany, Vistula Land, Russian Empire; now Poland) was a Russian official, an officer in the Special Corps of Gendarmes, later also director of the Warsaw Theatre Directorate and second husband of the Polish pianist Maria Kalergis.