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Sda protein domain information


Sda
structure of the sda antikinase
Identifiers
SymbolSda
PfamPF08970
InterProIPR015064
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

In molecular biology, the protein domain Sda is short for suppressor of dnaA or otherwise known as sporulation inhibitor A. It is found only in bacteria. This protein domain is highly important to cell survival. When starved of nutrients, the cell is under extreme stress so undergoes a series of reactions to increase the chances of survival. One method is to form endospores which can withstand a large amount of environmental pressure.[1] Sda protein domain is a checkpoint which prevents the formation of spores. The Sda domain affects cell signalling. It prevents the cell communicating the stress that it is under, which is crucial if the cell is to survive.

  1. ^ Burkholder WF; Kurtser I; Grossman AD (2001). "Replication initiation proteins regulate a developmental checkpoint in Bacillus subtilis". Cell. 104 (2): 269–79. doi:10.1016/s0092-8674(01)00211-2. hdl:1721.1/83916. PMID 11207367. S2CID 15048130.

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