Global InformationSaffold virus information
| Saffold virus | |
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Virus classification 
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| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Picornavirales |
| Family: | Picornaviridae |
| Genus: | Cardiovirus |
| Species: | Cardiovirus D
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| Virus: | Saffold virus
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Saffold virus (SAFV) is a single-stranded RNA human virus belonging to the family Picornaviridae. Discovered in 2007, it is the first human virus in the genus Cardiovirus and may provide a link to the development of multiple sclerosis or other serious diseases in humans.[1]
The Saffold virus was previously a member of the Theilovirus species but was re-classified in 2019 as an isolate of the species Cardiovirus D. It has shown to affect the gastrointestinal tract and respiratory systems, and is found to be present early in life.[2]
- ^ Kirkegaard, Karla; Zoll, Jan; Erkens Hulshof, Sandra; Lanke, Kjerstin; Verduyn Lunel, Frans; Melchers, Willem J. G.; Schoondermark-Van De Ven, Esther; Roivainen, Merja; Galama, Jochem M. D. (2009). Kirkegaard, Karla (ed.). "Saffold Virus, a Human Theiler's-Like Cardiovirus, is Ubiquitous and Causes Infection Early in Life". PLOS Pathogens. 5 (5): e1000416. doi:10.1371/journal.ppat.1000416. PMC 2670511. PMID 19412527.
- ^ Himeda, Toshiki; Ohara, Yoshiro (February 2012). "Saffold Virus, a Novel Human Cardiovirus with Unknown Pathogenicity". Journal of Virology. 86 (3): 1292–1296. doi:10.1128/JVI.06087-11. ISSN 0022-538X. PMC 3264344. PMID 22114344.