SYNPO information

SYNPO
Identifiers
Aliases	SYNPO, synaptopodin
External IDs	OMIM: 608155; MGI: 1099446; HomoloGene: 5274; GeneCards: SYNPO; OMA:SYNPO - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	150,659,207 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	60,793,214 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; apex of heart; ; Descending thoracic aorta; ; gastrocnemius muscle; ; Skeletal muscle tissue of rectus abdominis; ; ascending aorta; ; right coronary artery; ; right auricle; ; tendon of biceps brachii; ; left ventricle;
	Top expressed in
	ascending aorta; ; aortic valve; ; muscle of thigh; ; external carotid artery; ; tunica media of zone of aorta; ; lumbar spinal ganglion; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; cumulus cell; ; ankle joint;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; actin binding;
Cellular component	cytoplasm; perikaryon; cell junction; postsynaptic membrane; dendritic spine; plasma membrane; cell projection; synapse; cytoskeleton; membrane; postsynaptic density; bicellular tight junction; Z disc; nucleus; actin cytoskeleton; stress fiber; spine apparatus; Schaffer collateral - CA1 synapse; glutamatergic synapse;
Biological process	positive regulation of actin filament bundle assembly; regulation of stress fiber assembly; spine apparatus assembly; visual learning; regulation of long-term neuronal synaptic plasticity; modification of dendritic spine; postsynaptic modulation of chemical synaptic transmission; positive regulation of postsynaptic cytosolic calcium concentration;
	Sources:Amigo / QuickGO
Orthologs
	11346
	104027
	ENSG00000171992
	ENSMUSG00000043079
	Q8N3V7
	Q8CC35
	NM_001109974; NM_001166208; NM_001166209; NM_007286
	NM_001109975; NM_177340
	NP_001103444; NP_001159680; NP_001159681; NP_009217
	NP_001103445; NP_796314
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptopodin is a protein that in humans is encoded by the SYNPO gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171992 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043079 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mundel P, Heid HW, Mundel TM, Krüger M, Reiser J, Kriz W (Oct 1997). "Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes". The Journal of Cell Biology. 139 (1): 193–204. doi:10.1083/jcb.139.1.193. PMC 2139823. PMID 9314539.
^ Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
^ "Entrez Gene: SYNPO synaptopodin".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171992 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043079 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9314539-5] Mundel P, Heid HW, Mundel TM, Krüger M, Reiser J, Kriz W (Oct 1997). "Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes". The Journal of Cell Biology. 139 (1): 193–204. doi:10.1083/jcb.139.1.193. PMC 2139823. PMID 9314539.

[pmid10470851-6] Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.

[entrez-7] "Entrez Gene: SYNPO synaptopodin".

SYNPO information

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MAGI1