SUDS3 information

SUDS3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2N2H, 4ZQA
Identifiers
Aliases	SUDS3, SAP45, SDS3, SDS3 homolog, SIN3A corepressor complex component
External IDs	OMIM: 608250; MGI: 1919204; HomoloGene: 15906; GeneCards: SUDS3; OMA:SUDS3 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	118,418,033 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	117,254,178 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; buccal mucosa cell; ; palpebral conjunctiva; ; pancreatic epithelial cell; ; epithelium of colon; ; parotid gland; ; skin of arm; ; tonsil; ; germinal epithelium; ; bone marrow cells;
	Top expressed in
	spermatid; ; spermatocyte; ; saccule; ; neural layer of retina; ; blood; ; otic placode; ; otic vesicle; ; granulocyte; ; lens; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	histone deacetylase binding; protein binding; enzyme binding; histone deacetylase activity;
Cellular component	Sin3 complex; nucleoplasm; Sin3-type complex; nucleus; cytosol; nuclear body;
Biological process	regulation of transcription, DNA-templated; substantia nigra development; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of apoptotic process; negative regulation of transcription, DNA-templated; histone deacetylation; apoptotic process; protein deubiquitination; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	64426
	71954
	ENSG00000111707
	ENSMUSG00000066900
	Q9H7L9
	Q8BR65
	NM_022491
	NM_001122666; NM_178622
	NP_071936
	NP_001116138; NP_848737
	Wikidata
View/Edit Human	View/Edit Mouse

Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111707 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066900 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Alland L, David G, Shen-Li H, Potes J, Muhle R, Lee HC, Hou H, Chen K, DePinho RA (April 2002). "Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex". Molecular and Cellular Biology. 22 (8): 2743–50. doi:10.1128/MCB.22.8.2743-2750.2002. PMC 133736. PMID 11909966.
^ "Entrez Gene: SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000111707 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000066900 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11909966-5] Alland L, David G, Shen-Li H, Potes J, Muhle R, Lee HC, Hou H, Chen K, DePinho RA (April 2002). "Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex". Molecular and Cellular Biology. 22 (8): 2743–50. doi:10.1128/MCB.22.8.2743-2750.2002. PMC 133736. PMID 11909966.

[entrez-6] "Entrez Gene: SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)".

SUDS3 information

and 5 Related for: SUDS3 information

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Host cell factor C1

SIN3B

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SIN3A