SPRED2 information

SPRED2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JP2
Identifiers
Aliases	SPRED2, Spred-2, sprouty related EVH1 domain containing 2, NS14
External IDs	OMIM: 609292; MGI: 2150019; HomoloGene: 24918; GeneCards: SPRED2; OMA:SPRED2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	65,432,637 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	19,974,026 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; mucosa of sigmoid colon; ; ventricular zone; ; cartilage tissue; ; epithelium of colon; ; gonad; ; postcentral gyrus; ; prefrontal cortex; ; superior frontal gyrus; ; Brodmann area 46;
	Top expressed in
	tail of embryo; ; primitive streak; ; prefrontal cortex; ; cingulate gyrus; ; genital tubercle; ; hair follicle; ; primary motor cortex; ; hippocampus proper; ; cerebellar vermis; ; lobe of cerebellum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein kinase binding; protein serine/threonine kinase inhibitor activity; stem cell factor receptor binding;
Cellular component	cytoplasm; plasma membrane; transport vesicle membrane; membrane; cytoplasmic vesicle; cytosol;
Biological process	multicellular organism development; negative regulation of peptidyl-threonine phosphorylation; regulation of signal transduction; fibroblast growth factor receptor signaling pathway; regulation of protein deacetylation; positive regulation of DNA damage response, signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	200734
	114716
	ENSG00000198369
	ENSMUSG00000045671
	Q7Z698
	Q924S7
	NM_001128210; NM_181784
	NM_033523
	NP_001121682; NP_861449
	NP_277058
	Wikidata
View/Edit Human	View/Edit Mouse

Sprouty-related, EVH1 domain-containing protein 2 is a protein that in humans is encoded by the SPRED2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198369 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000045671 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SPRED2 sprouty-related, EVH1 domain containing 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198369 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045671 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SPRED2 sprouty-related, EVH1 domain containing 2".

SPRED2 information

and 5 Related for: SPRED2 information

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