SOX15 information

SOX15
Identifiers
Aliases	SOX15, SOX20, SOX26, SOX27, SRY-box 15, SRY-box transcription factor 15
External IDs	OMIM: 601297; MGI: 98363; HomoloGene: 74586; GeneCards: SOX15; OMA:SOX15 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	7,590,094 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,547,553 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; skin of abdomen; ; skin of leg; ; mucosa of pharynx; ; vagina; ; right hemisphere of cerebellum; ; olfactory zone of nasal mucosa; ; gonad; ; epithelium of esophagus;
	Top expressed in
	morula; ; blastocyst; ; morula; ; corneal stroma; ; transitional epithelium of urinary bladder; ; lip; ; secondary oocyte; ; zygote; ; esophagus; ; entorhinal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; chromatin binding; protein binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus;
Biological process	positive regulation of myoblast proliferation; cell differentiation; male gonad development; regulation of transcription, DNA-templated; positive regulation of satellite cell activation involved in skeletal muscle regeneration; negative regulation of striated muscle tissue development; regulation of transcription by RNA polymerase II; positive regulation of G0 to G1 transition; negative regulation of transcription by RNA polymerase II; chromatin organization; myoblast development; skeletal muscle tissue regeneration; positive regulation of transcription by RNA polymerase II; central nervous system development; neuron differentiation;
	Sources:Amigo / QuickGO
Orthologs
	6665
	20670
	ENSG00000129194
	ENSMUSG00000041287
	O60248
	P43267
	NM_006942
	NM_009235
	NP_008873
	NP_033261
	Wikidata
View/Edit Human	View/Edit Mouse

Protein SOX-15 is a protein that in humans is encoded by the SOX15 gene.^[5]^[6]^[7]

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000129194 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041287 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Meyer J, Wirth J, Held M, Schempp W, Scherer G (Jan 1997). "SOX20, a new member of the SOX gene family, is located on chromosome 17p13". Cytogenet Cell Genet. 72 (2–3): 246–9. doi:10.1159/000134200. PMID 8978787.
^ Critcher R, Stitson RN, Wade-Martins R, Easty DJ, Farr CJ (Oct 1998). "Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3". Cytogenet Cell Genet. 81 (3–4): 294–5. doi:10.1159/000015052. PMID 9730625. S2CID 46849443.
^ ^a ^b "Entrez Gene: SOX15 SRY (sex determining region Y)-box 15".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000129194 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041287 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8978787-5] Meyer J, Wirth J, Held M, Schempp W, Scherer G (Jan 1997). "SOX20, a new member of the SOX gene family, is located on chromosome 17p13". Cytogenet Cell Genet. 72 (2–3): 246–9. doi:10.1159/000134200. PMID 8978787.

[pmid9730625-6] Critcher R, Stitson RN, Wade-Martins R, Easty DJ, Farr CJ (Oct 1998). "Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3". Cytogenet Cell Genet. 81 (3–4): 294–5. doi:10.1159/000015052. PMID 9730625. S2CID 46849443.

[entrez-7] "Entrez Gene: SOX15 SRY (sex determining region Y)-box 15".

SOX15 information

and 5 Related for: SOX15 information

SOX15

List of human transcription factors

Induced pluripotent stem cell

SOX gene family

Reprogramming