SOSTDC1 information

SOSTDC1
Identifiers
Aliases	SOSTDC1, ECTODIN, USAG1, CDA019, DAND7, sclerostin domain containing 1
External IDs	OMIM: 609675; MGI: 1913292; HomoloGene: 9154; GeneCards: SOSTDC1; OMA:SOSTDC1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	16,530,580 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	36,368,451 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; hair follicle; ; parotid gland; ; lower lobe of lung; ; rectum; ; sperm; ; endothelial cell; ; vulva; ; right lung; ; lactiferous duct;
	Top expressed in
	molar; ; retinal pigment epithelium; ; sciatic nerve; ; lip; ; lateral recess; ; kidney; ; maxillary prominence; ; skin of back; ; skin of abdomen; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	BMP binding; BMP receptor activity;
Cellular component	extracellular region; extracellular space;
Biological process	pattern specification process; odontogenesis of dentin-containing tooth; hair follicle morphogenesis; mammary gland bud morphogenesis; negative regulation of cell fate commitment; Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; negative regulation of Wnt signaling pathway; BMP signaling pathway; negative regulation of BMP signaling pathway; negative regulation of myoblast differentiation; negative regulation of determination of dorsal identity;
	Sources:Amigo / QuickGO
Orthologs
	25928
	66042
	ENSG00000171243
	ENSMUSG00000036169
	Q6X4U4
	Q9CQN4
	NM_015464
	NM_025312
	NP_056279
	NP_079588
	Wikidata
View/Edit Human	View/Edit Mouse

Sclerostin domain-containing protein 1 is a protein that in humans is encoded by the SOSTDC1 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171243 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036169 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SOSTDC1 sclerostin domain containing 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171243 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036169 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SOSTDC1 sclerostin domain containing 1".