Ski/Dach domain-containing protein 1 is a protein that in humans is encoded by the SKIDA1 gene.[5] It is also known as C10orf140 and DLN-1. It has orthologs in vertebrates. It has two domains: the Ski/Sno/Dac domain and a domain of unknown function, DUF4854. It is associated with multiple types of cancer, like leukemia, ovarian cancer, and colon cancer.[6][7] It's predicted to be a nuclear protein.[8] It may interact with PRC2.[9][10]
^ abcGRCh38: Ensembl release 89: ENSG00000180592 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000054074 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"SKI/DACH domain-containing protein 1 [Homo sapiens]". NCBI. Retrieved 11 February 2019.
^Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, et al. (April 2013). "GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer". Nature Genetics. 45 (4): 362–70, 370e1-2. doi:10.1038/ng.2564. PMC 3693183. PMID 23535730.
^Cortes-Ciriano I, Lee S, Park WY, Kim TM, Park PJ (June 2017). "A molecular portrait of microsatellite instability across multiple cancers". Nature Communications. 8: 15180. Bibcode:2017NatCo...815180C. doi:10.1038/ncomms15180. PMC 5467167. PMID 28585546.
^Cite error: The named reference :4 was invoked but never defined (see the help page).
^Liefke R, Shi Y (2015-04-28). "The PRC2-associated factor C17orf96 is a novel CpG island regulator in mouse ES cells". Cell Discovery. 1: 15008. doi:10.1038/celldisc.2015.8. PMC 4860827. PMID 27462409.
^Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, et al. (October 2016). "A High-Density Map for Navigating the Human Polycomb Complexome". Cell Reports. 17 (2): 583–595. doi:10.1016/j.celrep.2016.08.096. hdl:20.500.11850/122094. PMID 27705803.
domain-containing protein 1 is a protein that in humans is encoded by the SKIDA1 gene. It is also known as C10orf140 and DLN-1. It has orthologs in vertebrates...
Repressive Complex 2 Associated Protein, a protein sharing a domain with SKIDA1 Electropop, a music genre This disambiguation page lists articles associated...
belongs to the Ski/Sno/Dac family, shared by SKI protein, Dachshund, and SKIDA1. Members of the Ski/Sno/Dac family share a domain that is roughly 100 amino...
found to have an inhibitory role in the TGF-beta signaling. Dachshund and SKIDA1 are also in the Ski/Sno/Dac family (InterPro: IPR003380, IPR023216. SKI...