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SKBR3 information


SkBr3 (also known as SK-BR-3) is a human breast cancer cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970 that is used in therapeutic research, especially in context of HER2 targeting.[1]

  1. ^ "SK-BR-3: Human Breast Cancer Cell Line (ATCC HTB-30)". Memorial Sloan-Kettering Cancer Center. Retrieved 18 June 2018.

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SKBR3

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SkBr3 (also known as SK-BR-3) is a human breast cancer cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970 that is used in therapeutic...

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Hair keratin

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associated with hair structures, KRT81 expression has been observed in the SKBR3 human breast cancer cell line and metastatic lymph nodes of breast carcinomas...

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List of breast cancer cell lines

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Adenocarcinoma Metastasis (pleural effusion) No No No Yes Yes Cellosaurus SkBr3 Invasive ductal carcinoma Metastasis (pleural effusion) No No Yes Yes No...

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HER2

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Erbin, GRB2, HSP90AA1, IL6ST, MUC1, PICK1 and PIK3R2, PLCG1, and SHC1. SkBr3 Cell Line, over-expresses HER2 GRCh38: Ensembl release 89: ENSG00000141736...

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Amentoflavone

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Synthase Inhibition by Amentoflavone Suppresses HER2/neu(erbB2) Oncogene in SKBR3 Human Breast Cancer Cells". Phytother. Res. 27 (5): 713–720. doi:10.1002/ptr...

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Neratinib

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Neratinib exerts only a modest effect on HER2 trafficking at IC50 of 6nM in SKBR3 cells. Neratinib is a 4-anilino-3-cyano quinoline derivative. Neratinib...

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Copine 3

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Copine3 with Jab1 activates downstream ErbB2 signaling and motility in SKBr3 breast cancer cells". Oncol. Rep. 35 (2): 1147–52. doi:10.3892/or.2015.4472...

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Free fatty acid receptor 4

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the knockdown of FFAR4 levels in cultured human MCF-7, MDA-MB-231, and SKBR3 breast cancer cells slowed their proliferation and increased their death...

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Photothermal therapy

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antibodies (anti-HER2 or anti-IgG) via PEG linkers. After incubation of SKBr3 cancer cells with the gold nanoshells, an 820 nm laser was used to irradiate...

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Mothers against decapentaplegic homolog 7

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mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line". Cell. Signal. 21 (6): 892–8. doi:10.1016/j.cellsig...

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