Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene.[5][6][7] The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000122335 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000015659 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ab"Entrez Gene: Serine active site containing 1". Retrieved 2012-07-24. This article incorporates text from this source, which is in the public domain.
^
"Protein SERAC1". Retrieved 2018-08-27. This article incorporates text available under the CC BY 4.0 license.
^
"UniProt: the universal protein knowledgebase". Nucleic Acids Research. 45 (D1): D158–D169. January 2017. doi:10.1093/nar/gkw1099. PMC 5210571. PMID 27899622.
active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a...
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This article incorporates text from this source, which is in the public domain.
This article incorporates text available under the CC BY 4.0 license.
