Protein-coding gene in the species Homo sapiens
SENP6 Identifiers Aliases SENP6 , SSP1, SUSP1, SUMO1/sentrin specific peptidase 6, SUMO specific peptidase 6External IDs OMIM: 605003; MGI: 1922075; HomoloGene: 9196; GeneCards: SENP6; OMA:SENP6 - orthologs Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q14.1 Start 75,601,509 bp[1] End 75,718,281 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 E1 Start 80,066,903 bp[2] End 80,144,953 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ventricular zone gastric mucosa right uterine tube sural nerve left ovary ganglionic eminence right ovary body of uterus left lobe of thyroid gland
Top expressed in genital tubercle tail of embryo ventricular zone zygote granulocyte ganglionic eminence gastric mucosa left lung lobe mucous cell of stomach epithelium of stomach
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
peptidase activity
cysteine-type peptidase activity
protein binding
hydrolase activity
SUMO-specific endopeptidase activity Cellular component
nucleus
nucleoplasm
cytosol
cytoplasm Biological process
protein desumoylation
protein modification by small protein removal
regulation of spindle assembly
protein sumoylation
proteolysis
regulation of kinetochore assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001100409
RefSeq (protein) NP_001093879
Location (UCSC) Chr 6: 75.6 – 75.72 Mb Chr 9: 80.07 – 80.14 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Sentrin-specific protease 6 is an enzyme that in humans is encoded by the SENP6 gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000112701 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034252 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Entrez Gene: SENP6 SUMO1/sentrin specific peptidase 6".
Last Update: 2023-12-27T04:30:18Z
Sentrin-specific protease 6 is an enzyme that in humans is encoded by the SENP6 gene. Ubiquitin-like molecules (UBLs), such as SUMO1, are structurally related...
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Last Update: 2024-05-13T20:47:11Z
1) SCZD5: schizophrenia disorder 5 SEN6: senescence (cellular)-related 6 SENP6 : SUMO1/sentrin specific peptidase 6 (6q14.1) SERAC1: serine active site...
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Last Update: 2024-05-27T03:38:27Z
tagged protein's function. In 2010, her team showed that the SUMO protein SENP6 was essential for assembling the kinetochore, another key structure that...
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Last Update: 2023-08-18T23:14:45Z
regarding its importance in maintaining adequate calcium levels in heart cells. SENP6 GRCh38: Ensembl release 89: ENSG00000116030 – Ensembl, May 2017 GRCm38:...
Word Count : 2334
Global Information
