SCRN3 information

SCRN3
Identifiers
Aliases	SCRN3, SES3, secernin 3
External IDs	OMIM: 614967 MGI: 1921866 HomoloGene: 11601 GeneCards: SCRN3
Gene location (Human)
Chr.	Chromosome 2 (human)
End	174,429,575 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	73,168,162 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; islet of Langerhans; ; prefrontal cortex; ; Achilles tendon; ; jejunal mucosa; ; rectum; ; oral cavity; ; monocyte; ; gastrocnemius muscle; ; amygdala;
	Top expressed in
	facial motor nucleus; ; triceps brachii muscle; ; quadriceps femoris muscle; ; intercostal muscle; ; knee joint; ; gastrocnemius muscle; ; temporal muscle; ; vastus lateralis muscle; ; sternocleidomastoid muscle; ; tibialis anterior muscle;
	More reference expression data
	n/a
Orthologs
	79634
	74616
	ENSG00000144306
	ENSMUSG00000008226
	Q0VDG4; Q0VDG5
	Q3TMH2
	NM_001193528; NM_024583
	NM_029022; NM_001355711
	NP_001180457; NP_078859; NP_078859.2
	NP_083298; NP_001342640
	Wikidata
View/Edit Human	View/Edit Mouse

Secernin-3 (SCRN3) is a protein that is encoded by the human SCRN3 gene. SCRN3 belongs to the peptidase C69 family and the secernin subfamily.^[5] As a part of this family, the protein is predicted to enable cysteine-type exopeptidase activity and dipeptidase activity, as well as be involved in proteolysis. It is ubiquitously expressed in the brain, thyroid, and 25 other tissues.^[6] Additionally, SCRN3 is conserved in a variety of species, including mammals, birds, fish, amphibians, and invertebrates.^[6] SCRN3 is predicted to be an integral component of the cytoplasm.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144306 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000008226 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "SCRN3 Gene - GeneCards | SCRN3 Protein | SCRN3 Antibody". www.genecards.org. Retrieved 2022-09-18.
^ ^a ^b "SCRN3 secernin 3 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-09-18.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000144306 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000008226 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:12-5] "SCRN3 Gene - GeneCards | SCRN3 Protein | SCRN3 Antibody". www.genecards.org. Retrieved 2022-09-18.

[:22-6] "SCRN3 secernin 3 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-09-18.