SAP scan images showing progression of AL amyloidosis kidney and liver involvement following chemotherapy
For the amyloid scan used in diagnosis of Alzheimer's disease, see Positron emission tomography § Neuroimaging.
A SAP scan is a type of nuclear medicine imaging test which uses iodine-123 (123I) and serum amyloid P component (SAP) to diagnose amyloidosis.[1][2]
In patients with amyloidosis, large deposits of SAP coat the affected organs, in addition to the low levels normally found in the blood stream.[3] The injected 123I-SAP localises specifically to amyloid deposits, showing up as hot spots in the image.[4]
^Lass, Piotr (2014). "Nuclear imaging of amyloidosis". Polish Journal of Radiology. 79: 222–227. doi:10.12659/PJR.890147. PMC 4111651.
^Sachchithanantham, S.; Wechalekar, A. D. (29 July 2013). "Imaging in systemic amyloidosis". British Medical Bulletin. 107 (1): 41–56. doi:10.1093/bmb/ldt021. PMID 23896486.
^"The SAP scan (AL amyloidosis)". Myeloma UK. Retrieved 28 July 2019.
^Sachchithanantham, S.; Wechalekar, A. D. (29 July 2013). "Imaging in systemic amyloidosis". British Medical Bulletin. 107 (1): 41–56. doi:10.1093/bmb/ldt021. PMID 23896486.
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