In the physiology of the kidney, renal blood flow (RBF) is the volume of blood delivered to the kidneys per unit time. In humans, the kidneys together receive roughly 25% of cardiac output, amounting to 1.2 - 1.3 L/min in a 70-kg adult male.
It passes about 94% to the cortex. RBF is closely related to renal plasma flow (RPF), which is the volume of blood plasma delivered to the kidneys per unit time.
Parameter
Value
renal blood flow
RBF = 1000 mL/min
hematocrit
HCT = 40%
glomerular filtration rate
GFR = 120 mL/min
renal plasma flow
RPF = 600 mL/min
filtration fraction
FF = 20%
urine flow rate
V = 1 mL/min
Sodium
Inulin
Creatinine
PAH
SNa = 150 mEq/L
SIn = 1 mg/mL
SCr = 0.01 mg/mL
SPAH =
UNa = 710 mEq/L
UIn = 150 mg/mL
UCr = 1.25 mg/mL
UPAH =
CNa = 5 mL/min
CIn = 150 mL/min
CCr = 125 mL/min
CPAH = 420 mL/min
ER = 90%
ERPF = 540 mL/min
While the terms generally apply to arterial blood delivered to the kidneys, both RBF and RPF can be used to quantify the volume of venous blood exiting the kidneys per unit time. In this context, the terms are commonly given subscripts to refer to arterial or venous blood or plasma flow, as in RBFa, RBFv, RPFa, and RPFv. Physiologically, however, the differences in these values are negligible so that arterial flow and venous flow are often assumed equal.
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