The Rehabilitation Trauma Center (RTC) at the Santa Clara Valley Medical Center (SCVMC) was founded in 1972 and is part of the only federally designated spinal cord injury center in Northern California. The center is one of the oldest spinal cord injury neurointensive care units in the United States and participated in the original National Institute on Disability and Rehabilitation Research Database collecting retrospective data to 1973.[1] The center is currently a ten-bed unit based in the Sobrato Pavilion's Respiratory Rehabilitation Unit (opened in 2017)[2] under the direction of Dr. Stephen L. McKenna.[3] The center is known for ventilator weaning after catastrophic neurological injury.[4][5][6][7]
The center is notable for clinical research in cellular therapies for neurological disease. In the first US clinical trial of hESC based therapies for spinal cord injury, 40% of the patients in the trial were enrolled through the Rehabilitation Trauma Center at Santa Clara Valley Medical Center.[8] In the subsequent dose escalation trial, the Center treated the first patient in the nation with complete (AIS-A) cervical spinal cord injury at the highest dose of 20 million cells of AST-OPC1 (oligodendrocyte progenitor cells); as well as, the first incomplete spinal cord injury (AIS-B).[9] The results of the 10 million cells cohort showed a doubling of the expected rate of recovery from traumatic spinal cord injury.[10] The center is a clinical program site in the Stanford Partnership for Spinal Cord Injury and Repair.[11]
The center is a core facility for Stanford residents and fellows in training. Stanford Physical Medicine and Rehabilitation residents learn the acute care of patients with catastrophic neurological injuries through consultation in the Rehabilitation Trauma Center.[12] The Stanford/VA Advanced Fellowship Program in Advanced Spinal Cord Injury Medicine features the center as a core training site for the management of acute neurological injury.[13]
^"National Spinal Cord Injury Statistical Center History 1973 to Present". Retrieved 1 January 2012.[permanent dead link]
^"Editorial: Sobrato Pavilion is spectacular addition to Valley Medical Center". The Mercury News. 2017-12-06. Retrieved 2018-01-14.
^"Stephen Lawrence McKenna MD". Stanford Profiles. Retrieved 2018-01-14.
^"Acute Ventilator Management and Weaning in Individuals with High Tetraplegia". Topics in Spinal Cord Injury Rehabilitation. Thomas Land. Archived from the original on 2012-07-17.
^"Bryan Stow out of ICU into Rehabilitation Trauma Center". foxsports.com. 2011-10-11. Retrieved 31 December 2011.
^FOX. "SF officer in critical condition moved to South Bay hospital". KTVU. Retrieved 2018-01-14.
^Louie, David (2017-05-24). "Cal rugby player paralyzed during game facing long road to recovery". ABC7 San Francisco. Retrieved 2018-01-15.
^Allday, Erin (14 December 2011). "Final Patient Enrolled in Spinal Cord Injury Clinical Trial". SFGate. San Francisco Chronicle. Archived from the original on 1 January 2012. Retrieved 1 January 2012.
^"Asterias Biotherapeutics Announces Treatment of First Spinal Cord Injury Patient with Maximum Dose of AST-OPC1 in SCiStar Clinical Trial". www.prnewswire.com. Retrieved 2018-01-15.
^"Asterias Biotherapeutics - A Global Leader In Regenerative Medicine". www.asteriasbiotherapeutics.com. Retrieved 2018-01-15.
^"Accelerating Discovery by Networking". Stanford Institute for Neuro-Innovation. Archived from the original on 23 April 2012. Retrieved 1 January 2012.
^"Stanford Physical Medicine and Rehabilitation Education". Archived from the original on 8 March 2012. Retrieved 1 January 2012.
^"Advanced Fellowship Program in Advanced Spinal Cord Injury Medicine". Retrieved 1 January 2012.
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