This article may be too technical for most readers to understand. Please help improve it to make it understandable to non-experts, without removing the technical details.(September 2009) (Learn how and when to remove this message)
A reeler mouse
A reeler is a mouse mutant, so named because of its characteristic "reeling" gait. This is caused by the profound underdevelopment of the mouse's cerebellum, a segment of the brain responsible for locomotion. The mutation is autosomal and recessive, and prevents the typical cerebellar folia from forming.
Cortical neurons are generated normally but are abnormally placed, resulting in disorganization of cortical laminar layers in the central nervous system. The reason is the lack of reelin, an extracellular matrix glycoprotein, which, during the corticogenesis, is secreted mainly by the Cajal–Retzius cells.
In the reeler neocortex, cortical plate neurons are aligned in a practically inverted fashion ("outside-in"). In the ventricular zone of the cortex fewer neurons have been found to have radial glial processes.[1] In the dentate gyrus of hippocampus, no characteristic radial glial scaffold is formed and no compact granule cell layer is established.[2] Therefore, the reeler mouse presents a good model in which to investigate the mechanisms of establishment of the precise neuronal network during development.
^Hartfuss E, Forster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Gotz M (2003). "Reelin signaling directly affects radial glia morphology and biochemical maturation". Development. 130 (19): 4597–609. doi:10.1242/dev.00654. hdl:10261/333510. PMID 12925587.
^Weiss KH, Johanssen C, Tielsch A, Herz J, Deller T, Frotscher M, Förster E (2003). "Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice". J. Comp. Neurol. 460 (1): 56–65. doi:10.1002/cne.10644. PMID 12687696. S2CID 25876741.
A reeler is a mouse mutant, so named because of its characteristic "reeling" gait. This is caused by the profound underdevelopment of the mouse's cerebellum...
of the reel. This allows projectionists running reel-to-reel to change over to the next reel on the other projector. A so-called "two-reeler" would have...
Reel to Reel is the debut solo studio album by American rapper Grand Puba. It was released on October 20, 1992, through Elektra Records. Recording sessions...
Belinda Haggett, Reeler was joined at the crease by Denise Annetts. The pair put on a women's Test record partnership of 309 runs, Reeler finishing on 110...
A cable reel is a round, drum-shaped object such as a spool used to carry various types of electrical wires. Cable reels, which can also be termed as drums...
reeling in Wiktionary, the free dictionary. Reeling may refer to Silk reeling "The Reeling", a song by American electronic band Passion Pit Reeling (book)...
guidelines for short film festivals to consider. Reel, for an explanation of the historic term "two-reeler" List of animated short series List of independent...
"Reel It In" (stylized in all caps) is a song by American rapper Aminé. It was sent to U.S. rhythmic contemporary radio on September 25, 2018 as the lead...
Reeler domain is a protein domain. Extracellular matrix (ECM) proteins play an important role in early cortical development, specifically in the formation...
Reel Stories, formerly Camp Reel Stories is a filmmaking program for girls and non-binary youth aged 12–19 years old. Reel Stories seeks to close a gender...
Virginia Reel can refer to any of the following: Virginia Reel (solitaire), a solitaire card game Virginia reel (dance), a folk dance Virginia Reel roller...
The Reels was an Australian rock band which formed in Dubbo, New South Wales in 1976. It disbanded in 1991, and reformed in 2007. Its 1981 song "Quasimodo's...
"The Reeling" is a song by American electronic band Passion Pit. It was released on May 11, 2009, as the first single from the band's debut studio album...
A fishing reel is a hand-cranked reel used in angling to wind and stow fishing line, typically mounted onto a fishing rod, but may also be used on compound...
A showreel (also known as a demo reel, sizzle reel, or work reel) is a short video showcasing a person's previous work used by people involved in filmmaking...
Catlett two-reeler, as Walter Hunting Trouble (1933) Walter Catlett two-reeler, as Walter Caliente Love (1933) Walter Catlett two-reeler, as Harrison...
ReelShort is a Chinese short-form video streaming app specializing in serialized dramas designed for mobile viewing. It is owned by COL Group, a publicly...
Reel People may refer to: Reel people, an ethnic group of South Sudan Reel People (film), a 1984 pornographic movie directed by Anthony Spinelli This disambiguation...
using this feature. Reels also integrates with existing Instagram filters and editing tools. In July 2020, Instagram rolled out Reels to India after TikTok...
Reeling in the Years is a television series shown on the Irish public broadcaster RTÉ. Each episode, running for about 25 minutes, reviews the events...
Reel Fishing is a series of fishing video games by Natsume Inc. The first game, Reel Fishing, was released for the PlayStation in 1996. Originally a localization...
Real to Reel may refer to: Real to Reel (Marillion album), 1984 Real to Reel (Starcastle album), 1978 Real to Reel (Tesla album), 2007 Real to Reel, a 1979...
The Reel-to-Reel Picture Show (also known as Reel-to-Reel) is an American game show that aired on PAX TV from August 31 to October 2, 1998. The show was...
hose reel is a cylindrical spindle made of either metal, fiberglass, or plastic and is used for storing a hose. The most common styles of hose reels are...
Global Information