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Ray David Owen information


Ray David Owen
Ray David Owen, 1979
Born(1915-10-30)October 30, 1915
Genesee, Wisconsin
DiedSeptember 21, 2014(2014-09-21) (aged 98)
Pasadena, California
EducationCarroll College, University of Wisconsin–Madison (Ph.D. 1941)
Known forGeneral Genetics (1952)
SpouseJune Weissenberg
ChildrenDavid, Griffin
AwardsNational Academy of Sciences, American Philosophical Society, Thomas Hunt Morgan Medal, Peter Medawar Medal and Prize
Scientific career
FieldsTeaching, immunology, organ transplantation
InstitutionsUniversity of Wisconsin, California Institute of Technology

Ray David Owen (October 30, 1915 – September 21, 2014) was a teacher and scientist whose discovery of unusual, “mixed,” red blood cell types in cattle twins in 1945 launched the fields of modern immunology and organ transplantation.[1][2][3][4] Owen's 1945 findings were published in the journal Science.[5] This observation demonstrated that self was “learned” by the immune system during development and paved the way for research involving induction of immune tolerance and early tissue grafting.[1][2] When Frank Macfarlane Burnet and Sir Peter Brian Medawar were awarded their 1960 Nobel Prize in Physiology or Medicine for the discovery of acquired immunological tolerance, Owen was not mentioned in the prize. However, in a letter to Owen, Medawar stated that he believed Owen should have also been included in the prize.[6] Owen also led the successful effort to admit women as California Institute of Technology (or Caltech) undergraduates.[1]

  1. ^ a b c Svitil, Kathy, "Remembering Ray D. Owen (1915-2014)", California Institute of Technology News, 9/23/2014
  2. ^ a b Mitchell, Bob, "In memoriam: Ray D. Owen discovered immune tolerance, paved the way for organ transplantation", University of Wisconsin-Madison Department of Communications, 9/26/2014
  3. ^ Brent, Leslie, "Ray David Owen (1915-2014): Geneticist and Immunologist. A Tribute to a True Pioneer", Transplantation, Volume 98, Number 12
  4. ^ Cancro, Michael P., December 2014, "Ray D. Owen, 1915-2014", Nature Immunology, Volume 15, Number 12
  5. ^ Owen RD, 1945, "Immunogenetic consequences of vascular anastomosis between bovine twins", Science, 102: 400
  6. ^ Crow, James F., November 1996, "A Golden Anniversary: Cattle Twins and Immune Tolerance, Genetics, 144: 855-859

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