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Raccoonpox virus information


Raccoonpox virus
Virus classification Edit this classification
(unranked): Virus
Realm: Varidnaviria
Kingdom: Bamfordvirae
Phylum: Nucleocytoviricota
Class: Pokkesviricetes
Order: Chitovirales
Family: Poxviridae
Genus: Orthopoxvirus
Species:
Raccoonpox virus

Raccoonpox virus (RCN) is a double-stranded DNA virus and a member of the orthopoxviruses in the family Poxviridae and subfamily Chordopoxvirinae which consists of eight genera: Avipoxvirus, Capripoxvirus, Leporipoxvirus, Molluscipoxvirus, Orthopoxvirus, Parapoxvirus, Suipoxvirus and Yatapoxvirus[1] Vertebrates are the natural host of Chordopoxvirinae subfamily viruses.[1] More specifically, raccoons are the natural hosts of RCN. RCN was isolated in 1961 from the upper respiratory tissues of 2 raccoons in a group of 92 observably healthy raccoons (Procyon lotor) trapped close to Aberdeen, Maryland.[2]

Of the 92 apparently healthy raccoons trapped near Aberdeen, Maryland in 1961, 22 had sera containing RCN HA1 antibodies. The sera partially cross-reacted with a vaccinia virus HA preparation, suggesting a close relation between the viruses.[3] Unlike the HA of other vaccinia-like viruses, the HA of RCN did not cross-react with monkeypox virus HA.[2] Though RPV is a close relative of vaccinia and cowpox viruses, it is distinct enough to be classified as a novel entity in the vaccinia/variola subgroup of poxviruses.[4]

  1. ^ a b Pastoret, P. P., & Vanderplasschen, A. (2003). Poxviruses as vaccine vectors [Electronic version]. Comparative Immunology, Microbiology, and Infectious Diseases, 26, 343-355.
  2. ^ a b Alexander, A. D.; Flyger, V.; Herman, Y. F.; Mcconnell, S. J.; Rothstein, N.; Yager, R. H. (1972). "Survey Of Wild Mammals In A Chesapeake Bay Area For Selected Zoonoses". Journal of Wildlife Diseases. 8 (2): 119–126. doi:10.7589/0090-3558-8.2.119. PMID 4336527.
  3. ^ Cite error: The named reference cavallaro was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference rockea was invoked but never defined (see the help page).

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Raccoonpox virus

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Raccoonpox virus (RCN) is a double-stranded DNA virus and a member of the orthopoxviruses in the family Poxviridae and subfamily Chordopoxvirinae which...

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Poxviridae

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; Stanford, Marianne M. (May 2010). "Potent oncolytic activity of raccoonpox virus in the absence of natural pathogenicity". Molecular Therapy. 18 (5):...

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