The quahog parasite unknown, or QPX, is a single-celled protist parasite in the class Labyrinthulomycota that affects hard clams (Mercenaria mercenaria; quahogs),[1] both cultured and wild.[2]
Parasites similar to QPX were first observed in New Brunswick, Canada, in 1959, when a mass death of hard clams was observed. Outbreaks have also occurred in Nova Scotia, Prince Edward Island, New York, New Jersey, Massachusetts, and Virginia, always only in quahog clams.[1][3]
Symptoms of QPX include chipping of the shells, mantle swelling, stunted shell growth and the development of nodules.[3][2]